北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第二临床医学院  > 眼科  > 期刊论文
学科主题: 临床医学
题名:
Fundus and histopathological study of radial optic neurotomy in the normal miniature pig eye
作者: Tao, Y; Jiang, YR; Li, XX; Yin, CY; Yao, M
刊名: ARCHIVES OF OPHTHALMOLOGY
发表日期: 2005-08-01
卷: 123, 期:8, 页:1097-1101
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: RETINAL VEIN OCCLUSION ; CIRCULATION ; ANASTOMOSIS
英文摘要:

Objective: To demonstrate the fundus and histopathological changes in the normal miniature pig eye after radial optic neurotomy.

Methods: Ophthalmoscopic examinations, fundus photography, and fluorescein angiography were performed on 12 eyes that underwent radial optic neurotomy, 5 normal eyes, and 7 eyes that underwent vitrectomy (from 12 pigs in total) preoperatively and 1, 7, 14, 30, and 90 days postoperatively. These eyes were enucleated 120 days postoperatively. Sixteen eyes (of 8 pigs in total) that underwent radial optic neurotomy were enucleated 1, 3, 7, and 48 days (2 pigs each time) postoperatively. The enucleated eye sections were stained with hematoxylineosin, Masson trichrome, and Luxol fast blue.

Results: The retina radial to the site of radial optic neurotomy darkened gradually with the increasing curvature of the major retinal arteries. The filling time intervals from the retinal artery to the retinal vein were prolonged. At the incision site, there was a loss of nerve fibers, which were subsequently replaced by collagenous tissue. No anastomotic vessels formed by the end of the study.

Conclusions: Postoperatively, the retinal circulation seemed somewhat sluggish compared with that seen preoperatively. Segmental retinal nerve atrophy eventually formed. The procedure itself may not be the sole factor for the formation of shunt vessels.

Clinical Relevance: To date, radial optic neurotomy is controversial and persuasive animal studies are lacking. In combining fluorescein angiography with histopathological examination, this study may be somewhat helpful.

语种: 英语
WOS记录号: WOS:000231236900010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53993
Appears in Collections:北京大学第二临床医学院_眼科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Peoples Hosp, Dept Ophthalmol, Beijing 100044, Peoples R China

Recommended Citation:
Tao, Y,Jiang, YR,Li, XX,et al. Fundus and histopathological study of radial optic neurotomy in the normal miniature pig eye[J]. ARCHIVES OF OPHTHALMOLOGY,2005,123(8):1097-1101.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Tao, Y]'s Articles
[Jiang, YR]'s Articles
[Li, XX]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Tao, Y]‘s Articles
[Jiang, YR]‘s Articles
[Li, XX]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace