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学科主题: 临床医学
题名:
Non-pharmaceutical factors for poor glycemic control in 13,970 Chinese women with drug-treated type 2 diabetes: a cross-sectional survey in 77 tertiary hospitals in four Chinese cities
作者: Lu, Juming1; Weng, Jianping2; Gu, Weijun1; Guo, Xiaohui3; Yang, Wenying4; Zou, Dajin5; Zhou, Zhiguang6; Zhu, Dalong7; Ji, Qiuhe8; Ji, Linong9; Yang, Xilin10
关键词: HbA(1c) goal ; hyperglycemia ; oral antidiabetic drugs
刊名: PATIENT PREFERENCE AND ADHERENCE
发表日期: 2014
DOI: 10.2147/PPA.S66915
卷: 8, 页:1161-1167
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: IMPAIRED GLUCOSE-TOLERANCE ; BLOOD-GLUCOSE ; VASCULAR COMPLICATIONS ; INSULIN-RESISTANCE ; SHORT STATURE ; LIFE-STYLE ; RISK ; MELLITUS ; PREVALENCE ; PREVENTION
英文摘要:

Background: Achieving good glycemic control improves clinical outcomes among patients with type 2 diabetes (T2D). This study aimed to explore non-pharmaceutical factors for poor glycemic control in Chinese women with T2D who used antidiabetic drug(s).

Methods: A cross-sectional survey was conducted in March to June 2011 in 77 top tertiary hospitals in Beijing, Shanghai, Tianjin, and Guangzhou, People′s Republic of China (the coverage rates of the 3A hospitals: 74.4%, 76%, 55%, and 29.3%, respectively). Of 29,502 patients with T2D who used oral antidiabetic drugs (OADs) alone or combined with insulin, 13,970 were women and used in the analysis. Logistic regression analysis was used to obtain odds ratios (ORs) and 95% confidence intervals (CIs) of factors for hyperglycemia defined as HbA1c (glycated hemoglobin) >= 77 mmol/mol (7.0%).

Results: The mean age was 60.3 (standard deviation 11.0) years, with a median of 4 (interquartile range 2-9) years of duration of diabetes, and 65.1% had hyperglycemia. In multivariable analysis, body height of >= 164 cm (OR 1.26, 95% CI 1.15-1.37) and obesity (OR 1.16, 95% CI 1.04-1.31) was associated with increased risk of hyperglycemia, while self-monitoring blood glucose (SMBG) decreased the risk of hyperglycemia (OR 0.78, 95% CI 0.73-0.84). Duration of diabetes >= 3 years (>= 3 to <6 years, OR 1.46, 95% CI 1.32-1.62; >= 6 to <10 years, OR 1.65, 95% CI 1.44-1.89), especially >= 10 years (OR 1.95, 95% CI 1.73-2.19), was associated with higher risks of hyperglycemia.

Conclusion: Body height >= 164 cm, obesity, and duration of diabetes >= 3 years increased while SMBG decreased risk of hyperglycemia in Chinese women with OAD-treated T2D.

语种: 英语
项目资助者: Novo Nordisk, People&prime ; s Republic of China
WOS记录号: WOS:000341633400002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54044
Appears in Collections:北京大学第一临床医学院_内分泌内科_期刊论文

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作者单位: 1.Sinojapan Friendship Hosp, Dept Endocrinol, Beijing, Peoples R China
2.Changhai Hosp Shanghai, Dept Endocrinol, Shanghai, Peoples R China
3.Chinese Peoples Liberat Army Gen Hosp, Dept Endocrinol, Beijing, Peoples R China
4.Sun Yat Sen Univ, Affiliated Hosp 3, Dept Endocrinol, Guangzhou 510275, Guangdong, Peoples R China
5.Peking Univ, Hosp 1, Dept Endocrinol, Beijing 100871, Peoples R China
6.Cent S Univ, Xiangya Hosp 2, Dept Endocrinol, Changsha, Hunan, Peoples R China
7.Nanjing Drum Tower Hosp, Dept Endocrinol, Nanjing, Jiangsu, Peoples R China
8.4th Mil Med Univ, Xijing Hosp, Dept Endocrinol, Xian, Peoples R China
9.Peking Univ, Peoples Hosp, Dept Endocrinol, Beijing 100871, Peoples R China
10.Tianjin Med Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Tianjin, Peoples R China

Recommended Citation:
Lu, Juming,Weng, Jianping,Gu, Weijun,et al. Non-pharmaceutical factors for poor glycemic control in 13,970 Chinese women with drug-treated type 2 diabetes: a cross-sectional survey in 77 tertiary hospitals in four Chinese cities[J]. PATIENT PREFERENCE AND ADHERENCE,2014,8:1161-1167.
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