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学科主题: 临床医学
题名:
Small gap sleeve bridging can improve the accuracy of peripheral nerve selective regeneration
作者: Kou, Yuhui1; Peng, Jianping2; Wu, Zhihong1; Yin, Xiaofeng2; Zhang, Peixun2; Zhang, Yu1; Weng, Xisheng1; Qiu, Guixing1; Jiang, Baoguo2
关键词: peripheral nerve ; regeneration ; selective ; small gap ; sleeve bridging
刊名: ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
发表日期: 2013-12-01
DOI: 10.3109/21691401.2012.762007
卷: 41, 期:6, 页:402-407
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]: Biotechnology & Applied Microbiology ; Engineering ; Materials Science
关键词[WOS]: MOTOR AXONS ; PREFERENTIAL REINNERVATION ; INJURY ; PATHWAYS ; REPAIR ; NEURON ; RECONSTRUCTION ; STIMULATION ; SPECIFICITY ; MATURATION
英文摘要:

The pure motor peripheral nerves animal model, obtained by ablating the dorsal root ganglions (DRGs), was used to investigate the accuracy of peripheral nerve selective regeneration using small gap sleeve bridging compared to epineurium neurorrhaphy. The results showed that the number of improperly regenerated motor axons in the distal stump and the misrouting ratio were significantly lower when the nerve transection was treated by small gap sleeve bridging. This suggests that more accurate reinnervation may be achieved by small gap sleeve bridging than by traditional epineurium neurorrhaphy.

语种: 英语
所属项目编号: 30625036 ; 2005CB522604 ; 30801169 ; A-2008-10 ; 31171150 ; 81171146 ; 30971526 ; 31040043
项目资助者: Chinese National Natural Science Fund for Outstanding Youth ; Chinese 973 Project Planning ; Chinese National Natural Science Youth Fund ; Beijing City Science &amp ; Technology New Star Classification ; Chinese National Natural Science Fund ; Chinese Educational Ministry New Century Excellent Talent Support Project
WOS记录号: WOS:000329843900008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54047
Appears in Collections:北京大学第二临床医学院_期刊论文

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作者单位: 1.Beijing Union Med Coll Hosp, Dept Orthoped, Beijing 100730, Peoples R China< !E Hosp, Dept Trauma Orthoped, Beijing 100871, Peoples R China

Recommended Citation:
Kou, Yuhui,Peng, Jianping,Wu, Zhihong,et al. Small gap sleeve bridging can improve the accuracy of peripheral nerve selective regeneration[J]. ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY,2013,41(6):402-407.
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