IR@PKUHSC  > 北京大学精神卫生研究所
学科主题精神卫生
Guidelines concordance of maintenance treatment in euthymic patients with bipolar disorder: Data from the national bipolar mania pathway survey (BIPAS) in mainland China
Wang, Zuowei1,2; Chen, Jun1; Zhang, Chen1; Gao, Keming3; Hong, Wu1; Xing, Mengjuan1; Wu, Zhiguo1; Yuan, Chengmei1; Huang, Jia1; Peng, Daihui1; Wang, Yong1; Lu, Weihong1; Yi, Zhenghui1; Yu, Xin4; Zhao, Jingping5; Fang, Yiru1
关键词Bipolar Disorder Euthymia Maintenance Treatment Guidelines Antidepressants
刊名JOURNAL OF AFFECTIVE DISORDERS
2015-08-15
DOI10.1016/j.jad.2015.04.028
182页:101-105
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Psychiatry
资助者National Natural Science Foundation of China ; Shanghai Key Medicine Specialties Program ; Hongkou District Key Medicine Specialties Program ; Training Plan for Excellent Academic Leaders of Shanghai Health System ; "12th Five-year Plan" of National Key Technologies RD Program ; National Key Clinical Disciplines at Shanghai Mental Health Center ; National Natural Science Foundation of China ; Shanghai Key Medicine Specialties Program ; Hongkou District Key Medicine Specialties Program ; Training Plan for Excellent Academic Leaders of Shanghai Health System ; "12th Five-year Plan" of National Key Technologies RD Program ; National Key Clinical Disciplines at Shanghai Mental Health Center
研究领域[WOS]Neurosciences & Neurology ; Psychiatry
关键词[WOS]PSYCHIATRY WFSBP GUIDELINES ; BIOLOGICAL TREATMENT ; WORLD FEDERATION ; SPECTRUM DISORDER ; CLINICAL-PRACTICE ; DEPRESSION ; PHARMACOTHERAPY ; PREVALENCE ; SOCIETIES ; ADHERENCE
英文摘要

Background: Although the treatment guidelines of bipolar disorders (BPD) have spread more than a decade, the concordance with evidence-based guidelines was typically low in routine clinical practice. This study is to present the data on the maintenance treatment of BPD in mainland China.

Methods: One thousand and twenty-three patients who had experienced a euthymia were eligible for entry into this survey on the maintenance treatment of BPD. Guidelines disconcordance was determined by comparing the medication(s) that patients were prescribed with the recommendations in the guidelines of the Canadian Network for Mood and Anxiety Treatments.

Results: Three hundred and sixty-four patients (35.6%) had not been prescribed with the maintenance treatment as guidelines recommendations, and 208 patients (20.3%) were prescribed with the antidepressants. A longer duration of BPD, a depressive episode at first onset, and a recent depressive or mixed episode significantly increased the risk for guidelines disconcordance and prescribing antidepressant. In contrast, a hospitalization history due to manic episode was associated with a significant decrease in the risk for guidelines disconcordance and prescribing antidepressant.

Limitation: This study was a cross-sectional and retrospective investigation based on medical records.

Conclusions: Considering the potentially hazardous effects of inappropriate treatment, individualized psychoeducational strategics for subjects with BPD are necessary to enhance treatment adherence and close the gap between guidelines and clinical practice in mainland China. (C) 2015 Elsevier B.V. All rights reserved.

语种英语
所属项目编号81301159 ; 91232719 ; ZK2012A12 ; XBR2013087 ; 2012BAI01B04 ; OMA-MH 2011-873
资助者National Natural Science Foundation of China ; Shanghai Key Medicine Specialties Program ; Hongkou District Key Medicine Specialties Program ; Training Plan for Excellent Academic Leaders of Shanghai Health System ; "12th Five-year Plan" of National Key Technologies RD Program ; National Key Clinical Disciplines at Shanghai Mental Health Center ; National Natural Science Foundation of China ; Shanghai Key Medicine Specialties Program ; Hongkou District Key Medicine Specialties Program ; Training Plan for Excellent Academic Leaders of Shanghai Health System ; "12th Five-year Plan" of National Key Technologies RD Program ; National Key Clinical Disciplines at Shanghai Mental Health Center
WOS记录号WOS:000356359700017
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54079
Collection北京大学精神卫生研究所
作者单位1.Peking Univ, Inst Mental Hlth, Beijing 100191, Peoples R China
2.Shanghai Jiao Tong Univ, Sch Med, Div Mood Disorders, Shanghai Mental Hlth Ctr, Shanghai 200030, Peoples R China
3.Hongkou Dist Mental Hlth Ctr Shanghai, Div Mood Disorders, Shanghai 200083, Peoples R China
4.Case Western Reserve Univ, Sch Med, Univ Hosp Case Med Ctr, Mood & Anxiety Clin Mood Disorders Program,Dept P, Cleveland, OH 44106 USA
5.Cent S Univ, Mental Hlth Inst, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China
Recommended Citation
GB/T 7714
Wang, Zuowei,Chen, Jun,Zhang, Chen,et al. Guidelines concordance of maintenance treatment in euthymic patients with bipolar disorder: Data from the national bipolar mania pathway survey (BIPAS) in mainland China[J]. JOURNAL OF AFFECTIVE DISORDERS,2015,182:101-105.
APA Wang, Zuowei.,Chen, Jun.,Zhang, Chen.,Gao, Keming.,Hong, Wu.,...&Fang, Yiru.(2015).Guidelines concordance of maintenance treatment in euthymic patients with bipolar disorder: Data from the national bipolar mania pathway survey (BIPAS) in mainland China.JOURNAL OF AFFECTIVE DISORDERS,182,101-105.
MLA Wang, Zuowei,et al."Guidelines concordance of maintenance treatment in euthymic patients with bipolar disorder: Data from the national bipolar mania pathway survey (BIPAS) in mainland China".JOURNAL OF AFFECTIVE DISORDERS 182(2015):101-105.
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