|Etiological features of cirrhosis inpatients in Beijing, China|
|Song Guang-jun; Feng Bo; Rao Hui-ying; Wei Lai|
|关键词||Etiology Cirrhosis Hepatitis b Hepatitis c Autoimmune Liver Disease Alcoholic Liver Disease|
|刊名||CHINESE MEDICAL JOURNAL|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, General & Internal|
|研究领域[WOS]||General & Internal Medicine|
|关键词[WOS]||HEPATITIS-B-VIRUS ; LIVER-DISEASE ; EPIDEMIOLOGY ; DIAGNOSIS ; MANAGEMENT ; INFECTION ; PACIFIC ; ASIA|
Background The etiological spectrum of cirrhosis has changed over the years, but our knowledge of it is limited. The present study aimed to investigate the etiological features of cirrhosis inpatients and their variation in the past 18 years in Beijing.
Methods A retrospective analysis was performed on all patients with cirrhosis diagnosed for the first time in Peking University People′s Hospital from January 1, 1993, to October 25, 2010. Data were analyzed using SPSS 20.0.
Results A total of 2119 cirrhosis inpatients were included in this study: 1412 (66.6%) male and 707 (33.4%) female. Chronic hepatitis B accounted for 58.7%; chronic hepatitis C for 7.6%; chronic hepatitis B and hepatitis C virus co-infection for 0.8% (16 cases); alcoholic liver disease for 9.4% (200 cases); and autoimmune diseases for 9.4% (199 cases). In the past 18 years, the percentage of chronic hepatitis B has decreased from 75.2% to 48.7%; alcoholic liver disease has increased from 5.1% to 10.6%; and autoimmune disease has increased from 2.2% to 12.9%. The percentages of chronic hepatitis B and alcoholic liver disease were higher among men, whereas the percentages of chronic hepatitis C, autoimmune diseases and cryptogenic cirrhosis were higher among women.
Conclusions Chronic hepatitis B was still the most common etiology of cirrhosis in China, but the percentage has been decreasing. The percentages of alcoholic liver disease and autoimmune diseases have been increasing. The etiological spectrum of cirrhosis inpatients differed significantly according to sex.
|作者单位||Peking Univ, Peoples Hosp, Inst Hepatol, Beijing Key Lab Hepatitis & Immunotherapy Liver D, Beijing 100044, Peoples R China|
|Song Guang-jun,Feng Bo,Rao Hui-ying,et al. Etiological features of cirrhosis inpatients in Beijing, China[J]. CHINESE MEDICAL JOURNAL,2013,126(13):2430-2434.|
|APA||Song Guang-jun,Feng Bo,Rao Hui-ying,&Wei Lai.(2013).Etiological features of cirrhosis inpatients in Beijing, China.CHINESE MEDICAL JOURNAL,126(13),2430-2434.|
|MLA||Song Guang-jun,et al."Etiological features of cirrhosis inpatients in Beijing, China".CHINESE MEDICAL JOURNAL 126.13(2013):2430-2434.|