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Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity
Yang, Wen-zhi1; Hu, Ying2; Wu, Wan-ying1; Ye, Min2; Guo, De-an1
关键词Panax Genus Panax Ginseng Panax Quinquefolius Panax Notoginseng Araliaceae Saponins Chemical Diversity Subtype Classification
刊名PHYTOCHEMISTRY
2014-10-01
DOI10.1016/j.phytochem.2014.07.012
106页:7-24
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]DAMMARANE-TYPE SAPONINS ; KOREAN RED GINSENG ; HEAT-PROCESSED GINSENG ; ORIENTAL PLANT DRUGS ; F H. CHEN ; FLOWER-BUDS ; TRITERPENE SAPONINS ; QUINQUEFOLIUM-L ; CA MEYER ; BIOACTIVE SAPONINS
英文摘要

The Panax genus is a crucial source of natural medicines that has benefited human health for a long time. Three valuable medicinal herbs, namely Panax ginseng, Panax quinquefolius, and Panax notoginseng, have received considerable interest due to their extensive application in clinical therapy, healthcare products, and as foods and food additives world-wide. Panax species are known to contain abundant levels of saponins, also dubbed ginsenosides, which refer to a series of dammarane or oleanane type triterpenoid glycosides. These saponins exhibit modulatory effects to the central nervous system and beneficial effects to patients suffering from cardiovascular diseases, and also have anti-diabetic and anti-tumor properties. To the end of 2012, at least 289 saponins were reported from eleven different Panax species. This comprehensive review describes the advances in the phytochemistry of the genus Panax for the period 1963-2012, based on the 134 cited references. The reported saponins can be classified into protopanaxadiol, protopanaxatriol, octillol, oleanolic acid, C17 side-chain varied, and miscellaneous subtypes, according to structural differences in sapogenins. The investigational history of Panax is also reviewed, with special attention being paid to the structural features of the six different subtypes, together with their H-1 and C-13 NMR spectroscopic characteristics which are useful for determining their structures and absolute configuration. (C) 2014 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000342258600001
项目编号BMU20110269
资助机构Program for New Century Excellent Talents in University from China Ministry of Education
引用统计
被引频次:62[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54160
专题北京大学药学院
北京大学药学院_天然药物学系
作者单位1.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Yang, Wen-zhi,Hu, Ying,Wu, Wan-ying,et al. Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity[J]. PHYTOCHEMISTRY,2014,106:7-24.
APA Yang, Wen-zhi,Hu, Ying,Wu, Wan-ying,Ye, Min,&Guo, De-an.(2014).Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity.PHYTOCHEMISTRY,106,7-24.
MLA Yang, Wen-zhi,et al."Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity".PHYTOCHEMISTRY 106(2014):7-24.
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