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学科主题: 临床医学
题名:
Detection of Infragenual Arterial Disease Using Non-Contrast-Enhanced MR Angiography in Patients With Diabetes
作者: Liu, Xin1; Zhang, Na1; Fan, Zhaoyang2; Feng, Fei3; Yang, Qi4; Zheng, Hairong1; Liu, Pengcheng3; Li, Debiao2
关键词: non-contrast-enhanced MR angiography ; diabetes ; peripheral vascular disease ; steady-state free precession ; flow-sensitive dephasing
刊名: JOURNAL OF MAGNETIC RESONANCE IMAGING
发表日期: 2014-12-01
DOI: 10.1002/jmri.24477
卷: 40, 期:6, 页:1422-1429
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: MAGNETIC-RESONANCE ANGIOGRAPHY ; NEPHROGENIC SYSTEMIC FIBROSIS ; PERIPHERAL VASCULAR-DISEASE ; DISTAL LOWER-EXTREMITIES ; FAST SPIN-ECHO ; FLOW ; GADODIAMIDE ; SSFP
英文摘要:

PurposeTo evaluate the diagnostic performance of a newly developed non-contrast-enhanced MR angiography (NCE-MRA) technique using flow-sensitive dephasing (FSD) prepared steady-state free precession (SSFP) for detecting calf arterial disease in patients with diabetes.

Materials and MethodsForty-five patients with diabetes who underwent routine contrast-enhanced MR angiography (CE-MRA) of lower extremities were recruited for NCE-MRA at the calf on a 1.5 Tesla MR system. Image quality evaluated on a 4-point scale and diagnostic performance for detecting more than 50% arterial stenosis were statistically analyzed, using CE-MRA as the standard of reference.

ResultsA total of 264 calf arterial segments were obtained in the 45 patients with 88 legs. The percentage of diagnostic arterial segments was all 98% for NCE- and CE-MRA. The image quality, SNR, CNR was 3.3, 177, 138, and 3.5, 103, 99, for NCE-MRA and CE-MRA, respectively. The average sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of NCE-MRA were 97%, 96%, 90%, 99%, and 96%, respectively on a per-segment basis and 90%, 84%, 82%, 91%, and 87%, respectively, on a per-patients basis.

ConclusionThe NCE-MRA technique demonstrates adequate image quality in the delineation of calf arteries and consistent diagnostic performance for detecting significant stenosis with CE-MRA in patients with diabetes. J. Magn. Reson. Imaging 2014;40:1422-1429. (c) 2013 Wiley Periodicals, Inc.

语种: 英语
所属项目编号: 81071147 ; 81120108012 ; 2011CB707903 ; JC201005270317A ; 1R01HL096119 ; AHA11POST7650043
项目资助者: National Natural Science Foundation of China ; National Basic Research Program 973 ; Key Project of Shenzhen Basic Research Program ; NIH ; American Heart Association
WOS记录号: WOS:000344786200019
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54187
Appears in Collections:北京大学深圳医院_期刊论文

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作者单位: 1.Chinese Acad Sci, Lauterbur Res Ctr Biomed Imaging, Shenzhen Inst Adv Technol, Shenzhen Key Lab MRI, Shenzhen, Peoples R China
2.Cedars Sinai Med Ctr, Biomed Imaging Res Inst, Los Angeles, CA 90048 USA
3.Peking Univ, Dept Radiol, Shenzhen Hosp, Shenzhen 518036, Peoples R China
4.Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing, Peoples R China

Recommended Citation:
Liu, Xin,Zhang, Na,Fan, Zhaoyang,et al. Detection of Infragenual Arterial Disease Using Non-Contrast-Enhanced MR Angiography in Patients With Diabetes[J]. JOURNAL OF MAGNETIC RESONANCE IMAGING,2014,40(6):1422-1429.
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