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CLINICAL CHARACTERISTICS AND OUTCOMES OF "SILENT" AND "NON-SILENT" PERITONITIS IN PATIENTS ON PERITONEAL DIALYSIS
Dong, Jie1; Luo, Suping; Xu, Rong; Chen, Yuan; Xu, Ying
关键词Peritonitis Outcomes
刊名PERITONEAL DIALYSIS INTERNATIONAL
2013
DOI10.3747/pdi.2011.00236
33期:1页:28-37
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]COMMUNITY-ACQUIRED PNEUMONIA ; GRAM-NEGATIVE PERITONITIS ; CHRONIC KIDNEY-DISEASE ; TRANSPORT CHARACTERISTICS ; CATHETER REMOVAL ; UNITED-STATES ; CHILDREN ; ADEQUACY ; RISK
英文摘要

Objectives: We compared the clinical characteristics and outcomes of "silent" peritonitis (meaning episodes without fever and abdominal pain) and "non-silent" peritonitis in patients on peritoneal dialysis (PD).

Methods: Our cohort study collected data about all peritonitis episodes occurring between January 2008 and April 2010. Disease severity score, demographics, and biochemistry and nutrition data were recorded at baseline. Effluent cell counts were examined at regular intervals, and the organisms cultured were examined. Treatment failure was defined as peritonitis-associated death or transfer to hemodialysis.

Results: Of 248 episodes of peritonitis occurring in 161 PD patients, 20.9% led to treatment failure. Of the 248 episodes, 51 (20.6%) were not accompanied by fever and abdominal pain. Patients with these silent peritonitis episodes tended to be older (p = 0.003). The baseline values for body mass index, triglycerides, and daily energy intake were significantly lower before silent peritonitis episodes than before non-silent episodes (p = 0.01, 0.003, and 0.001 respectively). Although silent peritonitis episodes were more often culture-negative and less often caused by gram-negative organisms, and although they presented with low effluent white cell counts on days 1 and 3, the risk for treatment failure in those episodes was not lower (adjusted odds ratio: 1.33; 95% confidence interval: 0.75 to 2.36; p = 0.33).

Conclusions: Silent peritonitis is not a rare phenomenon, especially in older patients on PD. Although these episodes were more often culture-negative, silent presentation was not associated with a better outcome. Perit Dial Int 2013; 33(1):28-37 www.PDIConnect.com epub ahead of print: 01 Aug 2012 doi: 10.3747/pdi.2011.00236

语种英语
WOS记录号WOS:000314186000005
资助机构Beijing Science and Technology Committee ; Scientific Research Foundation for Returned Scholars of Peking University ; Fresenius Kabi Deutschland GmbH ; Baxter Healthcare Corporation, China
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54192
专题北京大学第一临床医学院_肾脏内科
作者单位1.Peking Univ First Hosp, Div Renal, Dept Med, Beijing 100034, Peoples R China
2.Peking Univ, Inst Nephrol, Beijing 100871, Peoples R China
3.Minist Hlth China, Key Lab Renal Dis, Beijing, Peoples R China
4.Peking Univ, Minist Educ, Key Lab Chron Kidney Dis Prevent & Treatment, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Dong, Jie,Luo, Suping,Xu, Rong,et al. CLINICAL CHARACTERISTICS AND OUTCOMES OF "SILENT" AND "NON-SILENT" PERITONITIS IN PATIENTS ON PERITONEAL DIALYSIS[J]. PERITONEAL DIALYSIS INTERNATIONAL,2013,33(1):28-37.
APA Dong, Jie,Luo, Suping,Xu, Rong,Chen, Yuan,&Xu, Ying.(2013).CLINICAL CHARACTERISTICS AND OUTCOMES OF "SILENT" AND "NON-SILENT" PERITONITIS IN PATIENTS ON PERITONEAL DIALYSIS.PERITONEAL DIALYSIS INTERNATIONAL,33(1),28-37.
MLA Dong, Jie,et al."CLINICAL CHARACTERISTICS AND OUTCOMES OF "SILENT" AND "NON-SILENT" PERITONITIS IN PATIENTS ON PERITONEAL DIALYSIS".PERITONEAL DIALYSIS INTERNATIONAL 33.1(2013):28-37.
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