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Liuwei Dihuang Pills (a...a(3)ae degrees e >>"a) enhance the effect of Western medicine in treating type 2 diabetes: A meta-analysis of randomized controlled trials
Pu Run1; Geng Xiang-nan2; Yu Fei3; Liang Hui-gang4; Shi Lu-wen1
关键词Meta-analyses Liuwei Dihuang Pills Type 2 Diabetes Fasting Blood Glucose Postprandial Blood Glucose Hemoglobin A1c
刊名CHINESE JOURNAL OF INTEGRATIVE MEDICINE
2013-10-01
DOI10.1007/s11655-013-1591-7
19期:10页:783-791
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
英文摘要

Objective: To perform meta-analyses evaluating the efficacy of adding Liuwei Dihuang Pills (a...a(3)ae degrees e >>"a, LDP) to Western medicine in improving treatment outcomes for type 2 diabetes. Medline, PubMed, Cochrane Library, and Chinese databases, including the Chinese National Knowledge Infrastructure were searched to identify eligible studies; i.e., if the study involved a randomized clinical trial in which the experimental group combined LDP with Western drugs and the control group used the corresponding Western drugs alone to treat type 2 diabetes. Outcomes were measured in terms of fasting blood glucose (FBG), postprandial blood glucose (2hPG) and HbA1c level. Efficacy was also measured by using control and response rates. The combined odds ratio (OR), mean difference (MD), and 95% confidence intervals (95% CI) were calculated. Studies included in the analysis were less adequate than expected in terms of methodological quality. A total of 1,609 patients from 18 studies were included. We found that adding LDP can lower patients′ FBG (MD=0.54 mmol/L, 95% CI [0.15, 0.93], P=0.007), 2hPG (MD=1.05 mmol/L, 95% CI [0.29, 1.81], P < 0.01) and HbA1c (MD=0.23, 95% CI [0.02, 0.45], P=0.008). There were also improvements in treatment response rates (OR=3.41, 95% CI [2.38, 4.90], P < 0.01) and control rates (OR=2.47, 95% CI [1.91, 3.20], P < 0.01). Adding LDP to Western medicine might improve treatment outcomes of diabetes, including FBG, 2hPG, response rates and control rates.

语种英语
WOS记录号WOS:000325360000010
项目编号2009BAI76B030900
资助机构National Key Technology Research and Development Program of the People&prime ; s Republic of China
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54319
专题北京大学药学院
北京大学药学院_药事管理与临床药学系
作者单位1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Dept Pharm Adm & Clin Pharm, Beijing 100191, Peoples R China
2.Chinese Pharmaceut Assoc, Beijing 100022, Peoples R China
3.Peking Univ, Hosp 1, Beijing 100034, Peoples R China
4.E Carolina Univ, Ctr Healthcare Management Syst, Greenville, NC 27858 USA
推荐引用方式
GB/T 7714
Pu Run,Geng Xiang-nan,Yu Fei,et al. Liuwei Dihuang Pills (a...a(3)ae degrees e >>"a) enhance the effect of Western medicine in treating type 2 diabetes: A meta-analysis of randomized controlled trials[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2013,19(10):783-791.
APA Pu Run,Geng Xiang-nan,Yu Fei,Liang Hui-gang,&Shi Lu-wen.(2013).Liuwei Dihuang Pills (a...a(3)ae degrees e >>"a) enhance the effect of Western medicine in treating type 2 diabetes: A meta-analysis of randomized controlled trials.CHINESE JOURNAL OF INTEGRATIVE MEDICINE,19(10),783-791.
MLA Pu Run,et al."Liuwei Dihuang Pills (a...a(3)ae degrees e >>"a) enhance the effect of Western medicine in treating type 2 diabetes: A meta-analysis of randomized controlled trials".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 19.10(2013):783-791.
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