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学科主题: 药学
题名:
Liuwei Dihuang Pills (a...a(3)ae degrees e >>"a) enhance the effect of Western medicine in treating type 2 diabetes: A meta-analysis of randomized controlled trials
作者: Pu Run1; Geng Xiang-nan2; Yu Fei3; Liang Hui-gang4; Shi Lu-wen1
关键词: meta-analyses ; Liuwei Dihuang Pills ; type 2 diabetes ; fasting blood glucose ; postprandial blood glucose ; hemoglobin A1c
刊名: CHINESE JOURNAL OF INTEGRATIVE MEDICINE
发表日期: 2013-10-01
DOI: 10.1007/s11655-013-1591-7
卷: 19, 期:10, 页:783-791
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Integrative & Complementary Medicine
研究领域[WOS]: Integrative & Complementary Medicine
英文摘要:

Objective: To perform meta-analyses evaluating the efficacy of adding Liuwei Dihuang Pills (a...a(3)ae degrees e >>"a, LDP) to Western medicine in improving treatment outcomes for type 2 diabetes. Medline, PubMed, Cochrane Library, and Chinese databases, including the Chinese National Knowledge Infrastructure were searched to identify eligible studies; i.e., if the study involved a randomized clinical trial in which the experimental group combined LDP with Western drugs and the control group used the corresponding Western drugs alone to treat type 2 diabetes. Outcomes were measured in terms of fasting blood glucose (FBG), postprandial blood glucose (2hPG) and HbA1c level. Efficacy was also measured by using control and response rates. The combined odds ratio (OR), mean difference (MD), and 95% confidence intervals (95% CI) were calculated. Studies included in the analysis were less adequate than expected in terms of methodological quality. A total of 1,609 patients from 18 studies were included. We found that adding LDP can lower patients′ FBG (MD=0.54 mmol/L, 95% CI [0.15, 0.93], P=0.007), 2hPG (MD=1.05 mmol/L, 95% CI [0.29, 1.81], P < 0.01) and HbA1c (MD=0.23, 95% CI [0.02, 0.45], P=0.008). There were also improvements in treatment response rates (OR=3.41, 95% CI [2.38, 4.90], P < 0.01) and control rates (OR=2.47, 95% CI [1.91, 3.20], P < 0.01). Adding LDP to Western medicine might improve treatment outcomes of diabetes, including FBG, 2hPG, response rates and control rates.

语种: 英语
所属项目编号: 2009BAI76B030900
项目资助者: National Key Technology Research and Development Program of the People&prime ; s Republic of China
WOS记录号: WOS:000325360000010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54319
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Dept Pharm Adm & Clin Pharm, Beijing 100191, Peoples R China
2.Chinese Pharmaceut Assoc, Beijing 100022, Peoples R China
3.Peking Univ, Hosp 1, Beijing 100034, Peoples R China
4.E Carolina Univ, Ctr Healthcare Management Syst, Greenville, NC 27858 USA

Recommended Citation:
Pu Run,Geng Xiang-nan,Yu Fei,et al. Liuwei Dihuang Pills (a...a(3)ae degrees e &gt;&gt;"a) enhance the effect of Western medicine in treating type 2 diabetes: A meta-analysis of randomized controlled trials[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2013,19(10):783-791.
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