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Dioxyxanthones from Polygala hongkongensis and Their Cytotoxicity
Wu Jian-feng1; Tu Peng-fei2; Zhan Hai-tao1; Gao Jing-chun3
关键词Polygala Hongkongensis Polygalaceae Dioxyxanthone Polyhongkongenoxanthone a And b Cytotoxicity
刊名CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
2011-09-01
27期:5页:777-779
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]TENUIFOLIA WILLDENOW ; XANTHONE GLYCOSIDES ; ROOTS ; ANTIOXIDANTS ; ESTERS ; HEMSL ; ACID
英文摘要

Two new dioxyxanthones, polyhongkongenoxanthones A and B(1 and 2) were isolated from the herbs of Polygala hongkongensis, together with six known xanthones. Their structures were elucidated on the basis of chemical and spectroscopic evidence. The isolates were tested for their cytotoxicity against three tumor cell lines(HepG2, GLC-82 and MCF-7, HepG2=human hepatocellular carcinoma cells; GLC-82=human lung carcinoma cells; MCF-7= human breast carcinoma cells) by MTT assay, among which polyhongkongenoxanthone 13(2), 1,7-dihydroxy-2,3-methylenedioxyxanthone(3) and 1,7-dihydroxy-3,4,8-trimethoxyxanthone(6) are potential antitumor candidate due to their significant cytotoxic effects on the three cell lines.

语种英语
WOS记录号WOS:000296120800014
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54373
专题北京大学药学院
北京大学药学院_天然药物学系
作者单位1.Foshan Univ, Coll Med, Foshan 528000, Peoples R China
2.Peking Univ, Hlth Sci Ctr, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
3.City Univ Hongkong, Dept Biol & Chem, Hong Kong, Hong Kong, Peoples R China
推荐引用方式
GB/T 7714
Wu Jian-feng,Tu Peng-fei,Zhan Hai-tao,et al. Dioxyxanthones from Polygala hongkongensis and Their Cytotoxicity[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2011,27(5):777-779.
APA Wu Jian-feng,Tu Peng-fei,Zhan Hai-tao,&Gao Jing-chun.(2011).Dioxyxanthones from Polygala hongkongensis and Their Cytotoxicity.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,27(5),777-779.
MLA Wu Jian-feng,et al."Dioxyxanthones from Polygala hongkongensis and Their Cytotoxicity".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 27.5(2011):777-779.
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