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Bacterial vaginosis is conducive to the persistence of HPV infection
Guo, Y-I1; You, K.1; Qiao, J.1; Zhao, Y-M2; Geng, L.1
关键词Human Papillomavirus Hpv Bacterial Vaginosis Bv Persistence High-risk Hpv Follow-up
刊名INTERNATIONAL JOURNAL OF STD & AIDS
2012-08-01
DOI10.1258/ijsa.2012.011342
23期:8页:581-584
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Immunology ; Infectious Diseases
研究领域[WOS]Immunology ; Infectious Diseases
关键词[WOS]HUMAN-PAPILLOMAVIRUS INFECTION ; NATURAL-HISTORY ; CERVICAL-CANCER ; WOMEN ; DIAGNOSIS ; METAANALYSIS ; NEOPLASIA ; SMEARS ; CELLS
英文摘要

We investigated the effects of bacterial vaginosis (BV) on the outcomes of high-risk human papillomavirus infection (HR-HPV). BV was diagnosed on Papanicolaou-stained cytology slides of 707 HPV-positive patients. HR-HPV DNA expression was analysed using the Hybrid Capture II (HC-II) assay. Of the 707 HR-HPV-positive female patients, 298 (42.1%) exhibited clearance of HR-HPV. The remaining 409 patients had persistent HR-HPV infection. The persistent HR-HPV group and the clearing group had similar rates of BV at the beginning of the study. At the end of the study, the persistent HR-HPV group had a BV prevalence of 11.2% while the clearing group had a significant lower BV prevalence of 5.0%. A decreased clearance of HPV was found in women with current BV, compared with women without BV. Furthermore, the natural history of HPV was not affected by the HPV viral load or the BV prevalence at the beginning of the study (P>0.05). Bacterial vaginosis appears conducive to the persistence of HPV infection.

语种英语
WOS记录号WOS:000309297400010
引用统计
被引频次:22[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54380
专题北京大学第三临床医学院
北京大学第三临床医学院_妇产科
北京大学第三临床医学院_生殖医学中心
作者单位1.Peking Univ, Hosp 3, Dept Obstet & Gynecol, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Res Ctr Clin Epidemiol, Beijing 100191, Peoples R China
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Guo, Y-I,You, K.,Qiao, J.,et al. Bacterial vaginosis is conducive to the persistence of HPV infection[J]. INTERNATIONAL JOURNAL OF STD & AIDS,2012,23(8):581-584.
APA Guo, Y-I,You, K.,Qiao, J.,Zhao, Y-M,&Geng, L..(2012).Bacterial vaginosis is conducive to the persistence of HPV infection.INTERNATIONAL JOURNAL OF STD & AIDS,23(8),581-584.
MLA Guo, Y-I,et al."Bacterial vaginosis is conducive to the persistence of HPV infection".INTERNATIONAL JOURNAL OF STD & AIDS 23.8(2012):581-584.
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