IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
Treatment of Non-alcoholic Fatty Liver Disease by Qianggan Capsule ((sic))
Li Li1; Zhang Xiao-jin1; Lan Yu1; Xu Le3; Zhang Xue-zhi2; Wang Hua-hong2
关键词Non-alcoholic Fatty Liver Disease Chinese Medicinal Therapy Qianggan Capsule Polyene Phosphatidylcholine Capsule
刊名CHINESE JOURNAL OF INTEGRATIVE MEDICINE
2010-02-01
DOI10.1007/s11655-010-0023-1
16期:1页:23-27
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
英文摘要

Objective: To observe the therapeutic effect and safety of Qianggan Capsule ((sic), QGC) in treating non-alcoholic fatty liver disease (NAFLD), using polyene phosphatidylcholine capsule (PPC) as a reference. Methods: Eighty-eight patients with NAFLD were randomly assigned to two groups, 45 in the treatment group treated with QGC and 43 in the control group treated with PPC. The course of treatment lasted for 6 months. Changes in liver function, blood lipids, and iconographic indexes before and after treatment were observed, and clinical efficacy was evaluated. Results: In the treatment group, alanine aminotransferase (ALT) was lowered significantly from 56.02 +/- 32.59 IU/L before treatment to 38.27 +/- 22.68 IU/L after treatment, and CT liver/spleen ratio significantly increased from 0.69 +/- 0.18 to 0.91 +/- 0.25, showing statistical significance (P<0.05); in contrast, the corresponding changes of the two indexes in the control group were 56.56 +/- 26.33 IU/L to 49.67 +/- 26.22 IU/L, and 0.66 +/- 0.20 to 0.75 +/- 0.24, respectively, the pre-post treatment difference showing insignificant difference (P>0.05). No severe adverse reactions occurred during the whole treatment course. Conclusion: QGC is an effective and safe remedy for the treatment of NAFLD.

语种英语
WOS记录号WOS:000274265600007
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54390
Collection北京大学第一临床医学院
作者单位1.Beijing Jishuitan Hosp, Dept Gastroenterol, Beijing 100035, Peoples R China
2.Peking Univ, Hosp 1, Beijing 100034, Peoples R China
3.Beijing Hosp, Beijing 100730, Peoples R China
Recommended Citation
GB/T 7714
Li Li,Zhang Xiao-jin,Lan Yu,et al. Treatment of Non-alcoholic Fatty Liver Disease by Qianggan Capsule ((sic))[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2010,16(1):23-27.
APA Li Li,Zhang Xiao-jin,Lan Yu,Xu Le,Zhang Xue-zhi,&Wang Hua-hong.(2010).Treatment of Non-alcoholic Fatty Liver Disease by Qianggan Capsule ((sic)).CHINESE JOURNAL OF INTEGRATIVE MEDICINE,16(1),23-27.
MLA Li Li,et al."Treatment of Non-alcoholic Fatty Liver Disease by Qianggan Capsule ((sic))".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 16.1(2010):23-27.
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