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学科主题: 临床医学
题名:
Treatment of Non-alcoholic Fatty Liver Disease by Qianggan Capsule ((sic))
作者: Li Li1; Zhang Xiao-jin1; Lan Yu1; Xu Le3; Zhang Xue-zhi2; Wang Hua-hong2
关键词: non-alcoholic fatty liver disease ; Chinese medicinal therapy ; Qianggan Capsule ; polyene phosphatidylcholine capsule
刊名: CHINESE JOURNAL OF INTEGRATIVE MEDICINE
发表日期: 2010-02-01
DOI: 10.1007/s11655-010-0023-1
卷: 16, 期:1, 页:23-27
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Integrative & Complementary Medicine
研究领域[WOS]: Integrative & Complementary Medicine
英文摘要:

Objective: To observe the therapeutic effect and safety of Qianggan Capsule ((sic), QGC) in treating non-alcoholic fatty liver disease (NAFLD), using polyene phosphatidylcholine capsule (PPC) as a reference. Methods: Eighty-eight patients with NAFLD were randomly assigned to two groups, 45 in the treatment group treated with QGC and 43 in the control group treated with PPC. The course of treatment lasted for 6 months. Changes in liver function, blood lipids, and iconographic indexes before and after treatment were observed, and clinical efficacy was evaluated. Results: In the treatment group, alanine aminotransferase (ALT) was lowered significantly from 56.02 +/- 32.59 IU/L before treatment to 38.27 +/- 22.68 IU/L after treatment, and CT liver/spleen ratio significantly increased from 0.69 +/- 0.18 to 0.91 +/- 0.25, showing statistical significance (P<0.05); in contrast, the corresponding changes of the two indexes in the control group were 56.56 +/- 26.33 IU/L to 49.67 +/- 26.22 IU/L, and 0.66 +/- 0.20 to 0.75 +/- 0.24, respectively, the pre-post treatment difference showing insignificant difference (P>0.05). No severe adverse reactions occurred during the whole treatment course. Conclusion: QGC is an effective and safe remedy for the treatment of NAFLD.

语种: 英语
WOS记录号: WOS:000274265600007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54390
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Beijing Jishuitan Hosp, Dept Gastroenterol, Beijing 100035, Peoples R China
2.Peking Univ, Hosp 1, Beijing 100034, Peoples R China
3.Beijing Hosp, Beijing 100730, Peoples R China

Recommended Citation:
Li Li,Zhang Xiao-jin,Lan Yu,et al. Treatment of Non-alcoholic Fatty Liver Disease by Qianggan Capsule ((sic))[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2010,16(1):23-27.
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