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Synthesis of galactosyl and lactosyl derivatives as potential anti-metastasis compounds
Li, H; Li, Q; Cai, MS; Li, ZJ
关键词Alpha-galactosyl Trimannoside Beta-lactosyl Trimannoside Glycosylation Synthesis
刊名CARBOHYDRATE RESEARCH
2000-10-06
328期:4页:611-615
收录类别IC ; SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]MURINE MELANOMA-CELLS
英文摘要

Based on the known anti-metastasis activities of lactosides and galactosides, a galactosyl and a lactosyl trimannoside were prepared via the conventional Koenigs-Knorr and trichloroacetimidate methods, respectively. Through typical deblocking procedures, a tetrasaccharide alpha-D-Galp-(1-->2)-alpha-D-Manp-(1-->2)-alpha-D-Manp-(1-->6)-alpha-D-ManpOCH(3) and a pentasaccharide beta-D-Galp-(1-->4)-beta-D-Glcp-(1-->2)-alpha-D-Manp-(1-->2)-alpha-D-Manp-(1-->6)-alpha-D-ManpOCH(3) were obtained. (C) 2000 Elsevier Science Ltd. All rights reserved.

语种英语
WOS记录号WOS:000089779000020
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54426
专题北京大学药学院
作者单位Beijing Med Univ, Sch Pharmaceut Sci, Dept Bioorgan Chem, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Li, H,Li, Q,Cai, MS,et al. Synthesis of galactosyl and lactosyl derivatives as potential anti-metastasis compounds[J]. CARBOHYDRATE RESEARCH,2000,328(4):611-615.
APA Li, H,Li, Q,Cai, MS,&Li, ZJ.(2000).Synthesis of galactosyl and lactosyl derivatives as potential anti-metastasis compounds.CARBOHYDRATE RESEARCH,328(4),611-615.
MLA Li, H,et al."Synthesis of galactosyl and lactosyl derivatives as potential anti-metastasis compounds".CARBOHYDRATE RESEARCH 328.4(2000):611-615.
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