北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 期刊论文
学科主题: 临床医学
题名:
Identification of M Protein From Filter Paper Using Serum Protein and Immunofixation Electrophoresis
作者: Wu, Yonghua1; Yang, Xu1; Wang, Tiancheng1; Wang, Haining2; Li, Zhenrong1
关键词: Serum protein electrophoresis ; Immunofixation electrophoresis ; M (monoclonal) protein ; Filter paper
刊名: AMERICAN JOURNAL OF CLINICAL PATHOLOGY
发表日期: 2012-10-01
DOI: 10.1309/AJCPFY6HLIT6HMQN
卷: 138, 期:4, 页:604-608
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pathology
研究领域[WOS]: Pathology
关键词[WOS]: BLOOD SPOT SAMPLES ; MULTIPLE-MYELOMA ; MONOCLONAL GAMMOPATHIES ; STORAGE
英文摘要:

Serum protein electrophoresis (SPE) and immunofixation electrophoresis (IFE) are standard methods for detection and monitoring of monoclonal (M) proteins. However, these tests are rarely available in the remote areas, especially in developing countries. Transportation of fresh serum (FS) samples is also usually inconvenient. This study investigated M-protein identification using serum blot on filter paper (FP). SPE and IFE were performed on FS and FP specimens using the Sebia Hydrasys automated electrophoresis system. Statistical analyses were conducted to assess sample stability and agreement of FS vs FP. The FP method showed good agreement with the FS method. The r values for correlation of albumin levels-alpha(1), alpha(2), beta, and gamma (%)-between FP and FS samples in SPE were all more than 0.95 (P < .01). IFE displayed no significant difference between those 2 methods in the identification of M protein. The FP method demonstrated an accurate and reproducible alternative to FS for identification of M protein using SPE and IFE.

语种: 英语
WOS记录号: WOS:000309018000015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54433
Appears in Collections:北京大学第三临床医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Dept Lab Med, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Dept Endocrinol, Hosp 3, Beijing 100191, Peoples R China

Recommended Citation:
Wu, Yonghua,Yang, Xu,Wang, Tiancheng,et al. Identification of M Protein From Filter Paper Using Serum Protein and Immunofixation Electrophoresis[J]. AMERICAN JOURNAL OF CLINICAL PATHOLOGY,2012,138(4):604-608.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Wu, Yonghua]'s Articles
[Yang, Xu]'s Articles
[Wang, Tiancheng]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Wu, Yonghua]‘s Articles
[Yang, Xu]‘s Articles
[Wang, Tiancheng]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace