IR@PKUHSC  > 北京大学基础医学院  > 心血管所
学科主题基础医学
Prognostic value of coronary artery calcium score in patients with stable angina pectoris after percutaneous coronary intervention
Wang, Fang-Fang1; Han, Jiang-Li1; He, Rong1; Zeng, Xiang-Zhu2; Zhang, Fu-Chun1; Guo, Li-Jun1; Gao, Wei1
关键词Angina Coronary Angiography Multi-slice Computed Tomography Heart Catheterization Vascular Calcification
刊名JOURNAL OF GERIATRIC CARDIOLOGY
2014
DOI10.3969/j.issn.1671-5411.2014.02.006
11期:2页:113-119
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cardiac & Cardiovascular Systems ; Geriatrics & Gerontology
研究领域[WOS]Cardiovascular System & Cardiology ; Geriatrics & Gerontology
关键词[WOS]COMPUTED-TOMOGRAPHY ; ATHEROSCLEROTIC PLAQUE ; DISEASE ; CALCIFICATION ; PREDICTION ; CT ; PREVALENCE ; GUIDELINE ; REGISTRY ; EVENTS
英文摘要

Objectives To evaluate the prognostic value of the coronary artery calcium (CAC) score in patients with stable angina pectoris (SAP) who underwent percutaneous coronary intervention (PCI). Methods A total of 334 consecutive patients with SAP who underwent first PCI following multi-slice computer tomography (MSCT) were enrolled from our institution between January 2007 and June 2012. The CAC score was calculated according to the standard Agatston calcium scoring algorithm. Complex PCI was defined as use of high pressure balloon, kissing balloon and/or rotablator. Procedure-related complications included dissection, occlusion, perforation, no/slow flow and emergency coronary artery bypass grafting. Main adverse cardiac events (MACE) were defined as a combined end point of death, non-fatal myocardial infarction, target lesion revascularization and rehospitalization for cardiac ischemic events. Results Patients with a CAC score > 300 (n = 145) had significantly higher PCI complexity (13.1% vs. 5.8%, P = 0.017) and rate of procedure-related complications (17.2% vs. 7.4%, P = 0.005) than patients with a CAC score <= 300 (n = 189). After a median follow-up of 22.5 months (4-72 months), patients with a CAC score <= 300 differ greatly than those patients with CAC score > 300 in cumulative non-events survival rates (88.9 vs. 79.0%, Log rank 4.577, P = 0.032). After adjusted for other factors, the risk of MACE was significantly higher [hazard ratio (HR): 4.3, 95% confidence interval (95% CI): 2.4-8.2, P = 0.038] in patients with a CAC score > 300 compared to patients with a lower CAC score. Conclusions The CAC score is an independent predictor for MACE in SAP patients who underwent PCI and indicates complexity of PCI and procedure-related complications.

语种英语
WOS记录号WOS:000338766400004
项目编号2006BAI01A02
资助机构National Institute of Science in China ; Backbone Fund of Peking University Third Hospital
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54453
专题北京大学基础医学院_心血管所
北京大学第三临床医学院_心血管内科
作者单位1.Peking Univ, Key Lab Cardiovasc Mol Biol & Regulatory Peptide, Key Lab Mol Cardiovasc Sci, Dept Cardiol,Minist Hlth,Minist Educ,Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Radiol, Beijing 100191, Peoples R China
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GB/T 7714
Wang, Fang-Fang,Han, Jiang-Li,He, Rong,et al. Prognostic value of coronary artery calcium score in patients with stable angina pectoris after percutaneous coronary intervention[J]. JOURNAL OF GERIATRIC CARDIOLOGY,2014,11(2):113-119.
APA Wang, Fang-Fang.,Han, Jiang-Li.,He, Rong.,Zeng, Xiang-Zhu.,Zhang, Fu-Chun.,...&Gao, Wei.(2014).Prognostic value of coronary artery calcium score in patients with stable angina pectoris after percutaneous coronary intervention.JOURNAL OF GERIATRIC CARDIOLOGY,11(2),113-119.
MLA Wang, Fang-Fang,et al."Prognostic value of coronary artery calcium score in patients with stable angina pectoris after percutaneous coronary intervention".JOURNAL OF GERIATRIC CARDIOLOGY 11.2(2014):113-119.
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