北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 基础医学院  > 心血管所  > 期刊论文
学科主题: 基础医学
题名:
Prognostic value of coronary artery calcium score in patients with stable angina pectoris after percutaneous coronary intervention
作者: Wang, Fang-Fang1; Han, Jiang-Li1; He, Rong1; Zeng, Xiang-Zhu2; Zhang, Fu-Chun1; Guo, Li-Jun1; Gao, Wei1
关键词: Angina ; Coronary angiography ; Multi-slice computed tomography ; Heart catheterization ; Vascular calcification
刊名: JOURNAL OF GERIATRIC CARDIOLOGY
发表日期: 2014
DOI: 10.3969/j.issn.1671-5411.2014.02.006
卷: 11, 期:2, 页:113-119
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems ; Geriatrics & Gerontology
研究领域[WOS]: Cardiovascular System & Cardiology ; Geriatrics & Gerontology
关键词[WOS]: COMPUTED-TOMOGRAPHY ; ATHEROSCLEROTIC PLAQUE ; DISEASE ; CALCIFICATION ; PREDICTION ; CT ; PREVALENCE ; GUIDELINE ; REGISTRY ; EVENTS
英文摘要:

Objectives To evaluate the prognostic value of the coronary artery calcium (CAC) score in patients with stable angina pectoris (SAP) who underwent percutaneous coronary intervention (PCI). Methods A total of 334 consecutive patients with SAP who underwent first PCI following multi-slice computer tomography (MSCT) were enrolled from our institution between January 2007 and June 2012. The CAC score was calculated according to the standard Agatston calcium scoring algorithm. Complex PCI was defined as use of high pressure balloon, kissing balloon and/or rotablator. Procedure-related complications included dissection, occlusion, perforation, no/slow flow and emergency coronary artery bypass grafting. Main adverse cardiac events (MACE) were defined as a combined end point of death, non-fatal myocardial infarction, target lesion revascularization and rehospitalization for cardiac ischemic events. Results Patients with a CAC score > 300 (n = 145) had significantly higher PCI complexity (13.1% vs. 5.8%, P = 0.017) and rate of procedure-related complications (17.2% vs. 7.4%, P = 0.005) than patients with a CAC score <= 300 (n = 189). After a median follow-up of 22.5 months (4-72 months), patients with a CAC score <= 300 differ greatly than those patients with CAC score > 300 in cumulative non-events survival rates (88.9 vs. 79.0%, Log rank 4.577, P = 0.032). After adjusted for other factors, the risk of MACE was significantly higher [hazard ratio (HR): 4.3, 95% confidence interval (95% CI): 2.4-8.2, P = 0.038] in patients with a CAC score > 300 compared to patients with a lower CAC score. Conclusions The CAC score is an independent predictor for MACE in SAP patients who underwent PCI and indicates complexity of PCI and procedure-related complications.

语种: 英语
所属项目编号: 2006BAI01A02
项目资助者: National Institute of Science in China ; Backbone Fund of Peking University Third Hospital
WOS记录号: WOS:000338766400004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54453
Appears in Collections:基础医学院_心血管所_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
jgc-11-02-113.pdf(298KB)期刊论文作者接受稿限制开放 联系获取全文

作者单位: 1.Peking Univ, Key Lab Cardiovasc Mol Biol & Regulatory Peptide, Key Lab Mol Cardiovasc Sci, Dept Cardiol,Minist Hlth,Minist Educ,Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Radiol, Beijing 100191, Peoples R China

Recommended Citation:
Wang, Fang-Fang,Han, Jiang-Li,He, Rong,et al. Prognostic value of coronary artery calcium score in patients with stable angina pectoris after percutaneous coronary intervention[J]. JOURNAL OF GERIATRIC CARDIOLOGY,2014,11(2):113-119.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Wang, Fang-Fang]'s Articles
[Han, Jiang-Li]'s Articles
[He, Rong]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Wang, Fang-Fang]‘s Articles
[Han, Jiang-Li]‘s Articles
[He, Rong]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2018  北京大学医学部 - Feedback
Powered by CSpace