IR@PKUHSC  > 北京大学第三临床医学院  > 肾内科
学科主题临床医学
Peripheral Arterial Disease Predicts Overall and Cardiovascular Mortality in Peritoneal Dialysis Patients
Tian, Shun-Li1,2; Tian, Xin-Kui1; Han, Qing-Feng1; Wang, Tao1
关键词Pad Survival Atherosclerosis Cardiovascular Disease Esrd
刊名RENAL FAILURE
2012
DOI10.3109/0886022X.2012.696470
34期:8页:1010-1014
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]BLOOD-PRESSURE INDEX ; STAGE RENAL-DISEASE ; HEMODIALYSIS-PATIENTS ; RISK-FACTORS ; VASCULAR-DISEASE ; IMPACT ; PREVALENCE
英文摘要

Background: Peripheral arterial disease (PAD) is an important manifestation of systemic atherosclerosis and is common among dialysis patients. Cardiovascular disease (CVD) accounts for the leading cause of mortality in dialysis patients, and PAD has been found as a predictor for cardiovascular as well as overall mortality in general population. However, the study on the role of PAD in the prognosis of peritoneal dialysis patients is rather limited. Methods: Prevalent continuous ambulatory peritoneal dialysis patients over 60 years old were recruited in this study and were followed-up regularly to death or the end of the study. The diagnosis of PAD was based on ankle-brachial pressure index (ABI) < 0.9 or intermittent claudication. Univariate and multivariate Cox proportional hazard models were used to identify the risk factors for cardiovascular and overall mortality. Survival curves were estimated by the Kaplan-Meier method followed by log-rank test to compare the mortality rate between PAD and non-PAD patients. Results: One hundred and seventy-one patients were included and 62 (36%) had PAD complication. In the follow-up of 24.4 (median 34.6) months, 36 deaths were recorded: 19 from PAD group and 17 from non-PAD group. Twenty-one patients died due to CVD: 13 from PAD group and 8 from non-PAD group. The presence of PAD and serum albumin was found independently associated with cardiovascular and overall mortality using Cox proportional hazards model. Conclusion: PAD is very common in aged peritoneal dialysis patients and independently associated with both cardiovascular and overall mortality.

语种英语
WOS记录号WOS:000307438300012
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54466
Collection北京大学第三临床医学院_肾内科
作者单位1.Peking Univ, Div Nephrol, Hosp 3, Beijing 100083, Peoples R China
2.Tianjin Med Univ, Gen Hosp, Dept Geratol, Tianjin Geriatr Inst, Tianjin, Peoples R China
Recommended Citation
GB/T 7714
Tian, Shun-Li,Tian, Xin-Kui,Han, Qing-Feng,et al. Peripheral Arterial Disease Predicts Overall and Cardiovascular Mortality in Peritoneal Dialysis Patients[J]. RENAL FAILURE,2012,34(8):1010-1014.
APA Tian, Shun-Li,Tian, Xin-Kui,Han, Qing-Feng,&Wang, Tao.(2012).Peripheral Arterial Disease Predicts Overall and Cardiovascular Mortality in Peritoneal Dialysis Patients.RENAL FAILURE,34(8),1010-1014.
MLA Tian, Shun-Li,et al."Peripheral Arterial Disease Predicts Overall and Cardiovascular Mortality in Peritoneal Dialysis Patients".RENAL FAILURE 34.8(2012):1010-1014.
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