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学科主题: 临床医学
题名:
Peripheral Arterial Disease Predicts Overall and Cardiovascular Mortality in Peritoneal Dialysis Patients
作者: Tian, Shun-Li1,2; Tian, Xin-Kui1; Han, Qing-Feng1; Wang, Tao1
关键词: PAD ; survival ; atherosclerosis ; cardiovascular disease ; ESRD
刊名: RENAL FAILURE
发表日期: 2012
DOI: 10.3109/0886022X.2012.696470
卷: 34, 期:8, 页:1010-1014
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Urology & Nephrology
研究领域[WOS]: Urology & Nephrology
关键词[WOS]: BLOOD-PRESSURE INDEX ; STAGE RENAL-DISEASE ; HEMODIALYSIS-PATIENTS ; RISK-FACTORS ; VASCULAR-DISEASE ; IMPACT ; PREVALENCE
英文摘要:

Background: Peripheral arterial disease (PAD) is an important manifestation of systemic atherosclerosis and is common among dialysis patients. Cardiovascular disease (CVD) accounts for the leading cause of mortality in dialysis patients, and PAD has been found as a predictor for cardiovascular as well as overall mortality in general population. However, the study on the role of PAD in the prognosis of peritoneal dialysis patients is rather limited. Methods: Prevalent continuous ambulatory peritoneal dialysis patients over 60 years old were recruited in this study and were followed-up regularly to death or the end of the study. The diagnosis of PAD was based on ankle-brachial pressure index (ABI) < 0.9 or intermittent claudication. Univariate and multivariate Cox proportional hazard models were used to identify the risk factors for cardiovascular and overall mortality. Survival curves were estimated by the Kaplan-Meier method followed by log-rank test to compare the mortality rate between PAD and non-PAD patients. Results: One hundred and seventy-one patients were included and 62 (36%) had PAD complication. In the follow-up of 24.4 (median 34.6) months, 36 deaths were recorded: 19 from PAD group and 17 from non-PAD group. Twenty-one patients died due to CVD: 13 from PAD group and 8 from non-PAD group. The presence of PAD and serum albumin was found independently associated with cardiovascular and overall mortality using Cox proportional hazards model. Conclusion: PAD is very common in aged peritoneal dialysis patients and independently associated with both cardiovascular and overall mortality.

语种: 英语
WOS记录号: WOS:000307438300012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54466
Appears in Collections:北京大学第三临床医学院_肾内科_期刊论文

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作者单位: 1.Peking Univ, Div Nephrol, Hosp 3, Beijing 100083, Peoples R China
2.Tianjin Med Univ, Gen Hosp, Dept Geratol, Tianjin Geriatr Inst, Tianjin, Peoples R China

Recommended Citation:
Tian, Shun-Li,Tian, Xin-Kui,Han, Qing-Feng,et al. Peripheral Arterial Disease Predicts Overall and Cardiovascular Mortality in Peritoneal Dialysis Patients[J]. RENAL FAILURE,2012,34(8):1010-1014.
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