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学科主题临床医学
Age and gender variations in the management of ischaemic stroke in China
Huang, Yining2,3; Wang, Ji-Guang; Wei, Jade W.1,4; Headley, Alexander P.1,4; Wong, Lawrence K. S.5; Heeley, Emma L.1,4; Arima, Hisatomi1,4; Sun, Jian6; Li, Qiang1,4; Liu, Ming7; Li, Zhengyi8; Wu, Li′ e(9); Cheng, Yan10; Huang, Qifang3; Zhang, Shihong; Xu, En11; Yang, Qidong12; Lu, Chuanzhen13; Anderson, Craig S.1,4; ChinaQUEST Invest
关键词Acute Age China Clinical Practice Management Gender Stroke
刊名INTERNATIONAL JOURNAL OF STROKE
2010-10-01
DOI10.1111/j.1747-4949.2010.00460.x
5期:5页:351-359
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Peripheral Vascular Disease
研究领域[WOS]Cardiovascular System & Cardiology
关键词[WOS]QUALITY-OF-CARE ; TISSUE-PLASMINOGEN ACTIVATOR ; SEX-DIFFERENCES ; CARDIOVASCULAR-DISEASES ; INTRAVENOUS THROMBOLYSIS ; RT-PA ; REGISTRY ; MORTALITY ; OUTCOMES ; ADULTS
英文摘要

Background

Stroke is a major health issue in China.

Aims

We aimed to describe the management of patients admitted to hospitals in China with acute ischaemic stroke, and to determine whether there were any differences by age and gender.

Methods

Using a multicentre prospective hospital register across all eight major economic (geographic) regions in China, data on the socioeconomic characteristics, medical history, clinical features, and in-hospital investigations, management, and outcomes were collected on consecutive patients with acute stroke due to cerebral ischaemia during a 5-month period in 2006.

Results

Overall, traditional Chinese medicine and neuroprotectant use were remarkably high, with nearly 80% of patients receiving the former and > 70% receiving the latter in hospital. Length of hospital stay was also long (median duration 16-days). Multivariate analyses revealed no clinically important differences in management between the genders. For the age-specific analyses, there were significant trends of decreasing use of thrombolysis (P=0 center dot 04), warfarin (P=0 center dot 01), corticosteroids (P=0 center dot 03), and lipid-lowering therapy (P=0 center dot 001); however, more assisted feeding (P=0 center dot 004) and rising rates of disability and in-hospital complications occurred with increasing age.

Conclusions

New information is provided regarding the current state of ischaemic stroke management in China. Notably, there is high use of traditional Chinese medicine and neuroprotectants and long lengths of hospital stay. Similar to many other countries, differences in stroke care and management by age and gender also exist to a small extent in China.

语种英语
WOS记录号WOS:000281556600004
资助机构Macquarie Bank Foundation ; George Foundation ; AstraZeneca Pharmaceutical China ; AusAID ; George Institute for International Health ; Australian Postgraduate Award
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54495
专题北京大学第一临床医学院_神经内科
作者单位1.Tianjin Med Univ, Gen Hosp, Tianjin, Peoples R China
2.Ctr S Univ, Xiangya Hosp, Changsha, Hunan, Peoples R China
3.Huashan Hosp, Shanghai, Peoples R China
4.First Affiliated Hosp, Baotou Med Coll, Baotou, Peoples R China
5.Univ Sydney, Sydney, NSW 2006, Australia
6.George Inst China, Beijing, Peoples R China
7.Xian Traff Univ, Coll Med, Hosp 1, Xian, Peoples R China
8.Royal Prince Alfred Hosp, George Inst Global Hlth, Camperdown, NSW 2050, Australia
9.Peking Univ, Dept Neurol, Hosp 1, Beijing 100871, Peoples R China
10.Shanghai Jiao Tong Univ, Ctr Epidemiol Studies & Clin Trials, Ruijin Hosp, Sch Med, Shanghai 200030, Peoples R China
11.Chinese Univ Hong Kong, Prince Wales Hosp, Hong Kong, Hong Kong, Peoples R China
12.Sichuan Univ, Dept Neurol, W China Hosp, Chengdu 610064, Peoples R China
13.Second Affiliated Hosp, Guangzhou Med Coll, Guangzhou, Guangdong, Peoples R China
推荐引用方式
GB/T 7714
Huang, Yining,Wang, Ji-Guang,Wei, Jade W.,et al. Age and gender variations in the management of ischaemic stroke in China[J]. INTERNATIONAL JOURNAL OF STROKE,2010,5(5):351-359.
APA Huang, Yining.,Wang, Ji-Guang.,Wei, Jade W..,Headley, Alexander P..,Wong, Lawrence K. S..,...&ChinaQUEST Invest.(2010).Age and gender variations in the management of ischaemic stroke in China.INTERNATIONAL JOURNAL OF STROKE,5(5),351-359.
MLA Huang, Yining,et al."Age and gender variations in the management of ischaemic stroke in China".INTERNATIONAL JOURNAL OF STROKE 5.5(2010):351-359.
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