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学科主题: 临床医学
题名:
Clavispora lusitaniae and Chaetomium atrobrunneum as Rare Agents of Cutaneous Infection
作者: Zhang, Hao1; Ran, Yuping1; Li, Dongming2; Liu, Yongfang3; Xiang, Yun1; Zhang, Ruifeng1; Dai, Yaling1
关键词: Clavispora lusitaniae ; Chaetomium atrobrunneum ; Candida lusitaniae ; Opportunistic fungi ; Extracellular enzyme
刊名: MYCOPATHOLOGIA
发表日期: 2010-05-01
DOI: 10.1007/s11046-009-9266-9
卷: 169, 期:5, 页:373-380
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Mycology
研究领域[WOS]: Mycology
关键词[WOS]: CEREBRAL FUNGAL-INFECTIONS ; IN-VITRO ACTIVITIES ; CANDIDA-LUSITANIAE ; AMPHOTERICIN-B ; IMMUNOCOMPROMISED HOST ; PATHOGEN ; PATIENT ; TROPICALIS ; RESISTANCE ; FUNGEMIA
英文摘要:

We describe the first case of cutaneous infection caused by Chaetomium atrobrunneum and Clavispora lusitaniae in a one-and-a-half-year-old boy with acute and severe inflammation around his left eyelid. He presented to our outpatient center with a 6-day history and previously ineffective antibacterial therapy. Scanning electron microscopy (SEM) revealed hyphae and spores were on the surface of the crusty exudates and also penetrated into it, and the microbiology study further showed their characteristic cultural features. Fungal isolates were identified by the amplification and sequencing of the 26S RNA gene and of the ITS region, as C. lusitaniae and C. atrobrunneum. Up until now, most known clinical records of these rare species have shown them as agents of deep mycosis. Due to the emergency situation, medications were administered promptly and confirmed by subsequent fungal identification and successful therapeutic outcome. This article illustrates the importance of recognizing fungal infections, especially those caused by uncommon pathogens. Limitations in the routine identification procedures and therapeutic options of this emerging opportunistic agent are also discussed in this report.

语种: 英语
所属项目编号: 30570095
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000278067200007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54506
Appears in Collections:北京大学第三临床医学院_皮肤科_期刊论文

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作者单位: 1.Sichuan Univ, W China Hosp, Dept Dermatol, Chengdu 610064, Peoples R China
2.Peking Univ, Dept Dermatol, Hosp 3, Beijing 100871, Peoples R China
3.N Sichuan Med Coll, Affiliated Hosp, Dept Infect Dis, Nanchong, Peoples R China

Recommended Citation:
Zhang, Hao,Ran, Yuping,Li, Dongming,et al. Clavispora lusitaniae and Chaetomium atrobrunneum as Rare Agents of Cutaneous Infection[J]. MYCOPATHOLOGIA,2010,169(5):373-380.
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