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学科主题临床医学
Clavispora lusitaniae and Chaetomium atrobrunneum as Rare Agents of Cutaneous Infection
Zhang, Hao1; Ran, Yuping1; Li, Dongming2; Liu, Yongfang3; Xiang, Yun1; Zhang, Ruifeng1; Dai, Yaling1
关键词Clavispora Lusitaniae Chaetomium Atrobrunneum Candida Lusitaniae Opportunistic Fungi Extracellular Enzyme
刊名MYCOPATHOLOGIA
2010-05-01
DOI10.1007/s11046-009-9266-9
169期:5页:373-380
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Mycology
研究领域[WOS]Mycology
关键词[WOS]CEREBRAL FUNGAL-INFECTIONS ; IN-VITRO ACTIVITIES ; CANDIDA-LUSITANIAE ; AMPHOTERICIN-B ; IMMUNOCOMPROMISED HOST ; PATHOGEN ; PATIENT ; TROPICALIS ; RESISTANCE ; FUNGEMIA
英文摘要

We describe the first case of cutaneous infection caused by Chaetomium atrobrunneum and Clavispora lusitaniae in a one-and-a-half-year-old boy with acute and severe inflammation around his left eyelid. He presented to our outpatient center with a 6-day history and previously ineffective antibacterial therapy. Scanning electron microscopy (SEM) revealed hyphae and spores were on the surface of the crusty exudates and also penetrated into it, and the microbiology study further showed their characteristic cultural features. Fungal isolates were identified by the amplification and sequencing of the 26S RNA gene and of the ITS region, as C. lusitaniae and C. atrobrunneum. Up until now, most known clinical records of these rare species have shown them as agents of deep mycosis. Due to the emergency situation, medications were administered promptly and confirmed by subsequent fungal identification and successful therapeutic outcome. This article illustrates the importance of recognizing fungal infections, especially those caused by uncommon pathogens. Limitations in the routine identification procedures and therapeutic options of this emerging opportunistic agent are also discussed in this report.

语种英语
WOS记录号WOS:000278067200007
项目编号30570095
资助机构National Natural Science Foundation of China
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54506
专题北京大学第三临床医学院_皮肤科
北京大学临床肿瘤学院_肿瘤放疗科
作者单位1.Sichuan Univ, W China Hosp, Dept Dermatol, Chengdu 610064, Peoples R China
2.Peking Univ, Dept Dermatol, Hosp 3, Beijing 100871, Peoples R China
3.N Sichuan Med Coll, Affiliated Hosp, Dept Infect Dis, Nanchong, Peoples R China
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GB/T 7714
Zhang, Hao,Ran, Yuping,Li, Dongming,et al. Clavispora lusitaniae and Chaetomium atrobrunneum as Rare Agents of Cutaneous Infection[J]. MYCOPATHOLOGIA,2010,169(5):373-380.
APA Zhang, Hao.,Ran, Yuping.,Li, Dongming.,Liu, Yongfang.,Xiang, Yun.,...&Dai, Yaling.(2010).Clavispora lusitaniae and Chaetomium atrobrunneum as Rare Agents of Cutaneous Infection.MYCOPATHOLOGIA,169(5),373-380.
MLA Zhang, Hao,et al."Clavispora lusitaniae and Chaetomium atrobrunneum as Rare Agents of Cutaneous Infection".MYCOPATHOLOGIA 169.5(2010):373-380.
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