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学科主题: 临床医学
题名:
Fibroblastic rheumatism: An addition to fibromatosis
作者: Ji, Lanlan; Geng, Yan; Hao, Yanjie; Zhang, Zhuoli
关键词: Cutaneous nodules ; Polyarthritis ; Serological negative ; Myofibroblastic proliferation ; Fibromatosis
刊名: JOINT BONE SPINE
发表日期: 2011-10-01
DOI: 10.1016/j.jbspin.2011.03.008
卷: 78, 期:5, 页:519-521
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Rheumatology
研究领域[WOS]: Rheumatology
英文摘要:

Fibroblastic rheumatism (FR) is a rare rheumatologic entity of unknown etiology. It is characterized by symmetrical polyarthritis associated with multiple cutaneous nodules. Bone erosion can occur as the disease progresses and destructive arthropathy is not rare. We report on an 18-year-old man with FR who presented a 6-year history of cutaneous nodules localized at para-articular sites with only minimal oligoarthralgia on exertion. There was no visceral involvement, and all the routine and immunological tests were normal. The diagnosis of FR was confirmed by histological examination of a nodule, which composed of myofibroblastic proliferation and thickened collagen fibers. Most skin lesions resolved after treated with IFN-alpha, however there was sequelae of permanent disability due to the progressive bone erosion despite weekly methotrexate treatment. (C) 2011 Societe francaise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.

语种: 英语
WOS记录号: WOS:000296383600018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54582
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: Beijing Univ, Dept Rheumatol & Clin Immunol, Hosp 1, Beijing 100034, Peoples R China

Recommended Citation:
Ji, Lanlan,Geng, Yan,Hao, Yanjie,et al. Fibroblastic rheumatism: An addition to fibromatosis[J]. JOINT BONE SPINE,2011,78(5):519-521.
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