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学科主题临床医学
An analysis of patients receiving emergency CAG without PCI and the value of GRACE score in predicting PCI possibilities in NSTE-ACS patients
Zhou, Bo-Da1,2,3; Zu, Ling-Yun1,2,3; Mi, Lin1,2,3; Wang, Gui-Song1,2,3; Guo, Li-Jun1,2,3; Gao, Wei1,2,3
关键词Acute Coronary Syndrome Coronary Angiography Grace Score Percutaneous Coronary Intervention
刊名JOURNAL OF GERIATRIC CARDIOLOGY
2015
12期:3页:246-250
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cardiac & Cardiovascular Systems ; Geriatrics & Gerontology
研究领域[WOS]Cardiovascular System & Cardiology ; Geriatrics & Gerontology
关键词[WOS]ACUTE MYOCARDIAL-INFARCTION ; TASK-FORCE ; MANAGEMENT ; REGISTRY ; EVENTS ; DEATH
英文摘要

Background There are patients who underwent emergency coronary angiography (CAG) but did not receive percutaneous coronary intervention (PCI). The aim of this study was to analyze these reasons. Methods This is a single-center retrospective study. We recruited 201 consecutive patients who received emergency CAG but did not receive PCI. To investigate the value of the Global Registry of Acute Coronary Events (GRACE) score in predicting PCI possibilities in non-ST segment elevation acute coronary syndrome (NSTE-ACS) patients, we recruited 80 consecutive patients who presented with NSTE-ACS and received emergency CAG as well as emergency PCI. Results Among the 201 patients who received emergency CAG but did not receive PCI, 26% patients had final diagnosis other than coronary heart disease. In the patients with significant coronary artery stenosis, 23 patients (11.5%) were recommended to coronary artery bypass grafting (CABG), one patient (0.5%) refused PCI; 13 patients (6.5%) with significant thrombus burden were treated with glycoprotein IIb/IIIa receptor antagonist; 74 patients (36.8%) were treated with drug therapy because no severe stenosis (>70%) was present in the crime vessel. Moreover, 80 of the 201 patients were presented with NSTE-ACS (excluding those patients with final diagnosis other than coronary heart disease, excluding those patients planned for CABG treatment), referred as non PCI NSTE-ACS. When comparing their GRACE scores with 80 consecutive patients presented with NSTE-ACS who received emergency CAG as well as emergency PCI (referred as PCI NSTE-ACS), we found that PCI NSTE-ACS patients had significantly higher GRACE scores compared with non PCI NSTE-ACS patients. We then used Receiver Operator Characteristic Curve (ROC) to test whether the GRACE score is good at evaluating the possibilities of PCI in NSTE-ACS patients. The area under the curve was 0.854 +/- 0.030 (P < 0.001), indicating good predictive value. Furthermore, we analyzed results derived from ROC statistics, and found that a GRACE score of 125.5, as a cut-off, has high sensitivity and specificity in evaluating PCI possibilities in NSTE-ACS patients. Conclusions Our findings indicate that the GRACE score has predictive value in determining whether NSTE-ACS patients would receive PCI.

语种英语
WOS记录号WOS:000360017600011
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54584
专题北京大学第三临床医学院_心血管内科
作者单位1.Peking Univ, Hosp 3, Dept Cardiol, Beijing 100871, Peoples R China
2.Peking Univ, Minist Educ, Key Lab Mol Cardiovasc Sci, Beijing 100871, Peoples R China
3.Peking Univ, Hosp 3, Minist Hlth, Key Lab Cardiovasc Mol Biol & Regulatory Peptides, Beijing 100871, Peoples R China
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Zhou, Bo-Da,Zu, Ling-Yun,Mi, Lin,et al. An analysis of patients receiving emergency CAG without PCI and the value of GRACE score in predicting PCI possibilities in NSTE-ACS patients[J]. JOURNAL OF GERIATRIC CARDIOLOGY,2015,12(3):246-250.
APA Zhou, Bo-Da,Zu, Ling-Yun,Mi, Lin,Wang, Gui-Song,Guo, Li-Jun,&Gao, Wei.(2015).An analysis of patients receiving emergency CAG without PCI and the value of GRACE score in predicting PCI possibilities in NSTE-ACS patients.JOURNAL OF GERIATRIC CARDIOLOGY,12(3),246-250.
MLA Zhou, Bo-Da,et al."An analysis of patients receiving emergency CAG without PCI and the value of GRACE score in predicting PCI possibilities in NSTE-ACS patients".JOURNAL OF GERIATRIC CARDIOLOGY 12.3(2015):246-250.
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