北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 心血管内科  > 期刊论文
学科主题: 临床医学
题名:
An analysis of patients receiving emergency CAG without PCI and the value of GRACE score in predicting PCI possibilities in NSTE-ACS patients
作者: Zhou, Bo-Da1,2,3; Zu, Ling-Yun1,2,3; Mi, Lin1,2,3; Wang, Gui-Song1,2,3; Guo, Li-Jun1,2,3; Gao, Wei1,2,3
关键词: Acute coronary syndrome ; Coronary angiography ; GRACE score ; Percutaneous coronary intervention
刊名: JOURNAL OF GERIATRIC CARDIOLOGY
发表日期: 2015
卷: 12, 期:3, 页:246-250
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems ; Geriatrics & Gerontology
研究领域[WOS]: Cardiovascular System & Cardiology ; Geriatrics & Gerontology
关键词[WOS]: ACUTE MYOCARDIAL-INFARCTION ; TASK-FORCE ; MANAGEMENT ; REGISTRY ; EVENTS ; DEATH
英文摘要:

Background There are patients who underwent emergency coronary angiography (CAG) but did not receive percutaneous coronary intervention (PCI). The aim of this study was to analyze these reasons. Methods This is a single-center retrospective study. We recruited 201 consecutive patients who received emergency CAG but did not receive PCI. To investigate the value of the Global Registry of Acute Coronary Events (GRACE) score in predicting PCI possibilities in non-ST segment elevation acute coronary syndrome (NSTE-ACS) patients, we recruited 80 consecutive patients who presented with NSTE-ACS and received emergency CAG as well as emergency PCI. Results Among the 201 patients who received emergency CAG but did not receive PCI, 26% patients had final diagnosis other than coronary heart disease. In the patients with significant coronary artery stenosis, 23 patients (11.5%) were recommended to coronary artery bypass grafting (CABG), one patient (0.5%) refused PCI; 13 patients (6.5%) with significant thrombus burden were treated with glycoprotein IIb/IIIa receptor antagonist; 74 patients (36.8%) were treated with drug therapy because no severe stenosis (>70%) was present in the crime vessel. Moreover, 80 of the 201 patients were presented with NSTE-ACS (excluding those patients with final diagnosis other than coronary heart disease, excluding those patients planned for CABG treatment), referred as non PCI NSTE-ACS. When comparing their GRACE scores with 80 consecutive patients presented with NSTE-ACS who received emergency CAG as well as emergency PCI (referred as PCI NSTE-ACS), we found that PCI NSTE-ACS patients had significantly higher GRACE scores compared with non PCI NSTE-ACS patients. We then used Receiver Operator Characteristic Curve (ROC) to test whether the GRACE score is good at evaluating the possibilities of PCI in NSTE-ACS patients. The area under the curve was 0.854 +/- 0.030 (P < 0.001), indicating good predictive value. Furthermore, we analyzed results derived from ROC statistics, and found that a GRACE score of 125.5, as a cut-off, has high sensitivity and specificity in evaluating PCI possibilities in NSTE-ACS patients. Conclusions Our findings indicate that the GRACE score has predictive value in determining whether NSTE-ACS patients would receive PCI.

语种: 英语
所属项目编号: 81300076 ; 81400833 ; 7132195 ; DFCMDA201306
项目资助者: National Natural Science Foundation of China ; Beijing Natural Science Foundation ; Discovery Cardiovascular Research Grant, Chinese Medical Doctor Association
WOS记录号: WOS:000360017600011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54584
Appears in Collections:北京大学第三临床医学院_心血管内科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Hosp 3, Dept Cardiol, Beijing 100871, Peoples R China
2.Peking Univ, Minist Educ, Key Lab Mol Cardiovasc Sci, Beijing 100871, Peoples R China
3.Peking Univ, Hosp 3, Minist Hlth, Key Lab Cardiovasc Mol Biol & Regulatory Peptides, Beijing 100871, Peoples R China

Recommended Citation:
Zhou, Bo-Da,Zu, Ling-Yun,Mi, Lin,et al. An analysis of patients receiving emergency CAG without PCI and the value of GRACE score in predicting PCI possibilities in NSTE-ACS patients[J]. JOURNAL OF GERIATRIC CARDIOLOGY,2015,12(3):246-250.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhou, Bo-Da]'s Articles
[Zu, Ling-Yun]'s Articles
[Mi, Lin]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhou, Bo-Da]‘s Articles
[Zu, Ling-Yun]‘s Articles
[Mi, Lin]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace