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学科主题: 临床医学
题名:
Three-Dimensional Modeling of the Pelvic Floor Support Systems of Subjects with and without Pelvic Organ Prolapse
作者: Ren, Shuang1; Xie, Bing2; Wang, Jianliu2; Rong, Qiguo1
刊名: BIOMED RESEARCH INTERNATIONAL
发表日期: 2015
DOI: 10.1155/2015/845985
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
研究领域[WOS]: Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]: LEVATOR ANI MUSCLE ; MAGNETIC-RESONANCE IMAGES ; VAGINAL DELIVERY ; FINITE-ELEMENT ; PERINEAL BODY ; ANATOMY ; APPEARANCE ; DEFECTS
英文摘要:

The purpose of this study was to develop three-dimensional finite element models of the whole pelvic support systems of subjects with and without pelvic organ prolapse (POP) that can be used to simulate anterior and posterior wall prolapses. Magnetic resonance imaging was performed in one healthy female volunteer (55 years old, para 2) and one patient (56 years old, para 1) with anterior vaginal wall prolapse. Contours of the pelvic structures were traced by a trained gynecologist. Smoothing of the models was conducted and attachments among structures were established. Finite element models of the pelvic support system with anatomic details were established for both the healthy subject and the POP patient. The models include the uterus, vagina with cavity, cardinal and uterosacral ligaments, levator ani muscle, rectum, bladder, perineal body, pelvis, obturator internus, and coccygeal muscle. Major improvements were provided in the modeling of the supporting ligaments and the vagina with high anatomic precision. These anatomically accurate models can be expected to allow study of the mechanism of POP in more realistic physiological conditions. The resulting knowledge may provide theoretical help for clinical prevention and treatment of POP.

语种: 英语
所属项目编号: 2014-ME-01/02...22
项目资助者: Seeding Grant for Medicine and Engineering Sciences of Peking University
WOS记录号: WOS:000349748100001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54596
Appears in Collections:北京大学第二临床医学院_期刊论文

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作者单位: 1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Obstet Gynecol, Beijing 100871, Peoples R China

Recommended Citation:
Ren, Shuang,Xie, Bing,Wang, Jianliu,et al. Three-Dimensional Modeling of the Pelvic Floor Support Systems of Subjects with and without Pelvic Organ Prolapse[J]. BIOMED RESEARCH INTERNATIONAL,2015.
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