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学科主题: 药学
题名:
Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus
作者: Ning, LL; Han, J; Zhang, XY; Guo, HZ; Bi, KS; Guo, DA
关键词: biotransformation ; triptolide ; triptonide ; cell suspension cultures ; Catharanthus roseus
刊名: JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
发表日期: 2004-06-01
DOI: 10.1080/1028602031000135567
卷: 6, 期:2, 页:93-97
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: ASPERGILLUS-NIGER ; 11-TAXADIENE ; ARTEMISININ
英文摘要:

Catharanthus roseus cell suspension cultures were used to bioconvert both triptolide (1) and triptonide (2). The same reaction path was followed in both biotransformations. Two biotransformed products were obtained and their structures identified as triptriolide (3) and 12beta,13alpha-dihydroxytriptonide (4), respectively, from 1 and 2 . Product 4 is a new compound.

语种: 英语
WOS记录号: WOS:000186924600003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54696
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.State Drug Adm, Ctr Drug Evaluat, Beijing 100038, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
3.Shenyang Pharmaceut Univ, Shenyang 110016, Liaoning, Peoples R China

Recommended Citation:
Ning, LL,Han, J,Zhang, XY,et al. Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2004,6(2):93-97.
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