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Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus
Ning, LL; Han, J; Zhang, XY; Guo, HZ; Bi, KS; Guo, DA
关键词Biotransformation Triptolide Triptonide Cell Suspension Cultures Catharanthus Roseus
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2004-06-01
DOI10.1080/1028602031000135567
6期:2页:93-97
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]ASPERGILLUS-NIGER ; 11-TAXADIENE ; ARTEMISININ
英文摘要

Catharanthus roseus cell suspension cultures were used to bioconvert both triptolide (1) and triptonide (2). The same reaction path was followed in both biotransformations. Two biotransformed products were obtained and their structures identified as triptriolide (3) and 12beta,13alpha-dihydroxytriptonide (4), respectively, from 1 and 2 . Product 4 is a new compound.

语种英语
WOS记录号WOS:000186924600003
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54696
专题北京大学药学院
作者单位1.State Drug Adm, Ctr Drug Evaluat, Beijing 100038, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
3.Shenyang Pharmaceut Univ, Shenyang 110016, Liaoning, Peoples R China
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GB/T 7714
Ning, LL,Han, J,Zhang, XY,et al. Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2004,6(2):93-97.
APA Ning, LL,Han, J,Zhang, XY,Guo, HZ,Bi, KS,&Guo, DA.(2004).Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,6(2),93-97.
MLA Ning, LL,et al."Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 6.2(2004):93-97.
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