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学科主题: 临床医学
题名:
Sildenafil Improves Erectile Hardness in Chinese Men With Erectile Dysfunction: A Real-life Study Analyzed on Age Stratification
作者: Zhang, Kai; Xu, Ben; Liu, Defeng; Wang, Xiaofeng; Zhu, Jichuan; Deng, Chunhua; Jin, Jie; Jiang, Hui2
刊名: UROLOGY
发表日期: 2014-04-01
DOI: 10.1016/j.urology.2013.12.007
卷: 83, 期:4, 页:831-836
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Urology & Nephrology
研究领域[WOS]: Urology & Nephrology
关键词[WOS]: CITRATE VIAGRA((R)) ; SEXUAL INTERCOURSE ; SCORE ; QUESTIONNAIRE ; SATISFACTION ; OPTIMIZATION ; ASSOCIATION ; VALIDATION ; OUTCOMES
英文摘要:

OBJECTIVE To evaluate the clinical efficacy of sildenafil for the improvement of penile erection hardness in erectile dysfunction (ED) patients and to determine the relationship between this improvement in erection hardness and social and psychological functioning.

MATERIALS AND METHODS From 2007 to 2008, a total of 4507 men diagnosed with ED were enrolled from 46 centers in China; 4039 of these patients were treated with sildenafil and asked to complete the Erectile Function domain of the International Index of Erectile Function, Erection Hardness Score, and Quality of Erection Questionnaire. The patients were divided into 5 groups on the basis of their age (group A: 20-30 years; group B: 31-40 years; group C: 41-50 years; group D: 51-60 years; and group E: > 60 years).

RESULTS A total of 3837 (95.0%) patients completed the entire study. After sildenafil treatment, the vast majority (96.3%) of the men were able to achieve grade 3-4 erection hardness. Patients with a better baseline erection hardness were more able to achieve grade 4 hardness after treatment (P <. 001). Comparisons of the Erection Hardness Score improvement before and after treatment between the age-categorized groups also showed that the erection hardness improvement was much greater in men older than 50 years.

CONCLUSION Sildenafil can help the vast majority of Chinese ED patients achieve grade 3-4 erection hardness. Grade 4 hardness can improve the patients′ sexual life to a greater extent than grade 3 hardness. A marked improvement in erection hardness can be achieved in patients older than 50 years. Crown Copyright (C) 2014 Published by Elsevier Inc.

语种: 英语
WOS记录号: WOS:000333984000041
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54698
Appears in Collections:北京大学第一临床医学院_泌尿外科_期刊论文

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作者单位: 1.Peking Univ, Hosp 1, Dept Urol, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Urol, Beijing 100191, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Urol, Beijing 100191, Peoples R China
4.Sun Yat Sen Univ, Affiliated Hosp 1, Dept Urol, Guangzhou 510275, Guangdong, Peoples R China

Recommended Citation:
Zhang, Kai,Xu, Ben,Liu, Defeng,et al. Sildenafil Improves Erectile Hardness in Chinese Men With Erectile Dysfunction: A Real-life Study Analyzed on Age Stratification[J]. UROLOGY,2014,83(4):831-836.
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