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学科主题药学
Indoloquinazoline alkaloids from Euodia rutaecarpa and their cytotoxic activities
Huang, Xin; Zhang, You-Bo; Yang, Xiu-Wei
关键词Euodia Rutaecarpa Indoloquinazoline Alkaloids (7r Human Promyelocytic Leukemia Hl-60 Cell 8s)-7-hydroxy-8-methoxy-rutaecarpine (7r Human Gastric Carcinoma N-87 Cells 8s)-7-hydroxy-8-ethoxy-rutaecarpine
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2011
DOI10.1080/10286020.2011.602015
13期:11页:977-983
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]EVODIA-RUTAECARPA ; FRUITS ; FRUCTUS
英文摘要

Nine indoloquinazoline alkaloids (1-9) were isolated from the dried and nearly ripe fruits of Euodia rutaecarpa (Juss.) Benth. (Euodiae Fructus), along with limonin and beta-sitosterol. Their structures were elucidated on the basis of their spectroscopic data. Among them, compounds 1 and 2 were new compounds and characterized as (7R,8S)-7-hydroxy-8-methoxy-rutaecarpine and (7R,8S)-7-hydroxy-8-ethoxy-rutaecarpine, respectively, and 1-hydroxy-rutaecarpine (3) and (7R,8S)-7,8-dihydroxy-rutaecarpine (4) were isolated from Euodiae Fructus for the first time. The nine indoloquinazoline alkaloids were evaluated for their cytotoxic activities against human promyelocytic leukemia HL-60 cells and human gastric carcinoma N-87 cells.

语种英语
WOS记录号WOS:000299683500001
项目编号2011BAI07B08
资助机构National Key Technology R&amp ; D Program of China
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54704
专题北京大学药学院_天然药物学系
作者单位Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Huang, Xin,Zhang, You-Bo,Yang, Xiu-Wei. Indoloquinazoline alkaloids from Euodia rutaecarpa and their cytotoxic activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2011,13(11):977-983.
APA Huang, Xin,Zhang, You-Bo,&Yang, Xiu-Wei.(2011).Indoloquinazoline alkaloids from Euodia rutaecarpa and their cytotoxic activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,13(11),977-983.
MLA Huang, Xin,et al."Indoloquinazoline alkaloids from Euodia rutaecarpa and their cytotoxic activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 13.11(2011):977-983.
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