IR@PKUHSC  > 北京大学基础医学院  > 生理学与病理生理学系
学科主题基础医学
Interleukin-1 beta is involved in the pressor response of amygdaloid neurons excited by sodium glutamate
Lu, Y; Chen, W; Zou, CJ
关键词arcuate nucleus central amygdaloid nucleus interleukin-1 beta paraventricular nucleus
刊名NEUROREPORT
2002-03-25
13期:4页:559-562
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Neurosciences
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]NUCLEUS
英文摘要

The effects of interleukin-1beta in the paraventricular nucleus or caudal arcuate nucleus on hypertensive and tachycardiac responses induced by excitation of the central amygdaloid nucleus were studied. We observed that microinjection of sodium glutamate into central amygdaloid nucleus resulted in hypertension and tachycardia. Microinjection of interleukin-1beta into paraventricular nucleus or caudal arcuate nucleus induced significant pressor and tachycardiac responses while pretreatment with microinjection of rabbit anti-rat interleukin-1beta antibody into bilateral paraventricular nuclei or arcuate nuclei attenuated the hypertensive response induced by microinjection of 40 nmol sodium glutamate into central amygdaloid nucleus. The above results suggest that the pressor effect of central amygdaloid nucleus is mediated by interleukin-1beta in paraventricular nucleus or arcuate nucleus.

语种英语
WOS记录号WOS:000174971300039
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54724
Collection北京大学基础医学院_生理学与病理生理学系
作者单位1.Peking Univ, Hlth Sci Ctr, Dept Physiol, Beijing 100083, Peoples R China
2.Peking Univ, Inst Cardiovasc Res, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Lu, Y,Chen, W,Zou, CJ. Interleukin-1 beta is involved in the pressor response of amygdaloid neurons excited by sodium glutamate[J]. NEUROREPORT,2002,13(4):559-562.
APA Lu, Y,Chen, W,&Zou, CJ.(2002).Interleukin-1 beta is involved in the pressor response of amygdaloid neurons excited by sodium glutamate.NEUROREPORT,13(4),559-562.
MLA Lu, Y,et al."Interleukin-1 beta is involved in the pressor response of amygdaloid neurons excited by sodium glutamate".NEUROREPORT 13.4(2002):559-562.
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