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学科主题: 临床医学
题名:
Value of sympathetic skin response test in the early diagnosis of diabetic neuropathy
作者: Huang, YN; Jia, ZR; Shi, X; Sun, XR
关键词: diabetic neuropathy ; peripheral nervous system disease ; electrophysiology sympathetic ; skin response ; sympathetic nervous system
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2004-09-01
卷: 117, 期:9, 页:1317-1320
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: SMALL-FIBER NEUROPATHY ; MELLITUS
英文摘要:

Background Diabetic neuropathy is common in diabetes mellitus. The early stage of diabetic neuropathy is often symptomless and difficult to be treated. The aim of this study was to assess the correlation between the results of the sympathetic skin response (SSR) test and the development of diabetic neuropathy, and explore the use of SSR as an objective basis for the early diagnosis of diabetic neuropathy.

Methods The latencies and amplitudes of initiation and of the N and P waves were determined by SSR testing of the extremities of 80 diabetic patients and 30 healthy controls.

Results The latencies of initiation and of the N and P waves were significantly ( P < 0.001) longer in diabetic patients than in the controls, while there was no significant difference in the amplitudes ( P > 0.05). All but two patients (97.5%) demonstrated abnormal SSR in at least one limb.

Conclusions SSR can detect early dysfunction of the small sympathetic fibers in people affected by diabetes mellitus, and may be a useful electrophysiological test for the early diagnosis of diabetic neuropathy.

语种: 英语
WOS记录号: WOS:000224145700008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54764
Appears in Collections:北京大学第一临床医学院_神经内科_期刊论文

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作者单位: Peking Univ, Hosp 1, Dept Neurol, Beijing 100034, Peoples R China

Recommended Citation:
Huang, YN,Jia, ZR,Shi, X,et al. Value of sympathetic skin response test in the early diagnosis of diabetic neuropathy[J]. CHINESE MEDICAL JOURNAL,2004,117(9):1317-1320.
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