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学科主题: 临床医学
题名:
Comparative analysis on the diagnosis and treatments of multisegment intramedullary spinal cord tumors between the different age groups
作者: Wang, Zhen-yu1; Sun, Jian-jun1; Xie, Jing-cheng1; Li, Zhen-dong1; Ma, Chang-cheng1; Liu, Bin1; Chen, Xiao-dong1; Liao, Hung-I2; Yu, Tao1; Zhang, Jia1
关键词: Spinal cord ; Intramedullary tumor ; Multisegments ; Years ; Initial symptoms ; Histological classification
刊名: NEUROSURGICAL REVIEW
发表日期: 2012
DOI: 10.1007/s10143-011-0345-2
卷: 35, 期:1, 页:85-92
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Surgery
研究领域[WOS]: Neurosciences & Neurology ; Surgery
关键词[WOS]: SURGICAL-TREATMENT ; SURGERY ; HEMANGIOBLASTOMAS ; RADIOTHERAPY ; ASTROCYTOMA ; EPENDYMOMAS ; ADULTS
英文摘要:

Multisegment intramedullary spinal cord tumors (MSICT) are a special type of spinal cord tumor. Up to now, no comparative clinical study of MSICT has been performed according to different age groups. Seventy-seven patients underwent microsurgery for MSICT. As grouped with two different methods, the parametric and nonparametric data of MSICT and patients were comparatively analyzed using statistically correlative methods. Forty-eight patients were males and 29 were females, ranging in age from 4 to 64 years (mean, 32.9 years). Among the six groups, being divided with intervals of 10 years, the whole difference in the initial symptoms of patients (Z=17.4, P=0.004) and in the histological classification of tumors (Z=12.5, P=0.03) was statistically significant, respectively. Neurodevelopmental tumor and benign glioma predominated in adolescents and decreased in frequency into adulthood where ependymoma became more predominant. In the 25 years old grouping method, there were 27 adolescent and 50 adult patients. The difference in initial symptoms of patients (Z=-2.08, P=0.04) was statistically significant between the two groups. Pain with motor weakness and gait deterioration predominated in adolescents and decreased in frequency into adulthood where sensory disturbances became more predominant.

语种: 英语
所属项目编号: BSD-09-6-11 ; 74496-01
项目资助者: Science Foundation of Ministry of Education of China ; Science Foundation of Peking University Third Hospital
WOS记录号: WOS:000301665100015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54841
Appears in Collections:北京大学第三临床医学院_神经外科_期刊论文

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作者单位: 1.Peking Univ, Dept Neurosurg, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Dept Orthoped, Hosp 3, Beijing 100871, Peoples R China

Recommended Citation:
Wang, Zhen-yu,Sun, Jian-jun,Xie, Jing-cheng,et al. Comparative analysis on the diagnosis and treatments of multisegment intramedullary spinal cord tumors between the different age groups[J]. NEUROSURGICAL REVIEW,2012,35(1):85-92.
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