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学科主题: 临床医学
题名:
Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China
作者: Yang, H.3; Wei, Y.3; Gao, X.3; Xu, X.2; Fan, L.4; He, J.5; Hu, Y.6; Liu, X.7; Chen, X.8; Yang, Z.9; Zhang, C.1; China Natl GDM Survey Working Grp
关键词: China ; gestational diabetes ; pregnancy ; risk factor
刊名: DIABETIC MEDICINE
发表日期: 2009-11-01
DOI: 10.1111/j.1464-5491.2009.02845.x
卷: 26, 期:11, 页:1099-1104
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Endocrinology & Metabolism
研究领域[WOS]: Endocrinology & Metabolism
关键词[WOS]: MATERNAL HYPERGLYCEMIA ; INCREASING PREVALENCE ; SPONTANEOUS-ABORTION ; ETHNICITY ; CITY
英文摘要:

Aims

To determine the incidence of gestational diabetes mellitus (GDM) in China and to further identify population specific risk factors for GDM.

Methods

Following a universal GDM screening recommendation, 16 286 pregnant women who underwent a 50-g glucose challenge test from 18 cities in China were followed up through pregnancy. GDM was confirmed by oral glucose tolerance test according to American Diabetes Association criteria.

Results

The incidence of GDM was 4.3%. Previously reported risk factors for GDM, including advanced maternal age, pre-pregnancy obesity and family history of diabetes, were strongly associated with an elevated GDM risk. Moreover, after the adjustment for the above-mentioned risk factors, a history of recurrent vulvovaginal candidiasis, residency in south China and a history of spontaneous abortion were significantly associated with an increased GDM risk; adjusted odds ratio (OR) [95% confidence interval (95% CI)] were 1.97 (1.39, 2.80), 1.84 (1.59-2.13), and 1.46 (1.12, 1.91), respectively.

Conclusions

In this large study of GDM in Chinese women, advanced maternal age, pre-pregnancy overweight or obesity and family history of diabetes were confirmed to be risk factors. In addition, a history of recurrent vulvovaginal candidiasis or spontaneous abortion and residency in south China appeared to be novel risk factors in this population.

语种: 英语
所属项目编号: 91000-242156028
项目资助者: national &prime ; 211&prime ; Project Peking University Evidence-Based Medicine Group ; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health
WOS记录号: WOS:000271493900004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54901
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.W China Second Univ Hosp, Chengdu, Peoples R China
2.Tianjin Cent Hosp Obstet & Gynecol, Tianjin, Peoples R China
3.Peking Univ, Hosp 3, Beijing 100871, Peoples R China
4.Shanghai First Peoples Hosp, Shanghai, Peoples R China
5.Beijing Obstet & Gynecol Hosp, Beijing, Peoples R China
6.Nanjing Drum Tower Hosp, Nanjing, Peoples R China
7.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Div Epidemiol Stat & Prevent Res, NIH, Rockville, MD 20852 USA
8.Peking Univ, Hosp 1, Dept Obstet & Gynecol, Beijing 100871, Peoples R China
9.Zhejiang Univ, Sch Med, Womens Hosp, Hangzhou 310003, Zhejiang, Peoples R China

Recommended Citation:
Yang, H.,Wei, Y.,Gao, X.,et al. Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China[J]. DIABETIC MEDICINE,2009,26(11):1099-1104.
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