IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China
Yang, H.3; Wei, Y.3; Gao, X.3; Xu, X.2; Fan, L.4; He, J.5; Hu, Y.6; Liu, X.7; Chen, X.8; Yang, Z.9; Zhang, C.1; China Natl GDM Survey Working Grp
关键词China Gestational Diabetes Pregnancy Risk Factor
刊名DIABETIC MEDICINE
2009-11-01
DOI10.1111/j.1464-5491.2009.02845.x
26期:11页:1099-1104
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Endocrinology & Metabolism
研究领域[WOS]Endocrinology & Metabolism
关键词[WOS]MATERNAL HYPERGLYCEMIA ; INCREASING PREVALENCE ; SPONTANEOUS-ABORTION ; ETHNICITY ; CITY
英文摘要

Aims

To determine the incidence of gestational diabetes mellitus (GDM) in China and to further identify population specific risk factors for GDM.

Methods

Following a universal GDM screening recommendation, 16 286 pregnant women who underwent a 50-g glucose challenge test from 18 cities in China were followed up through pregnancy. GDM was confirmed by oral glucose tolerance test according to American Diabetes Association criteria.

Results

The incidence of GDM was 4.3%. Previously reported risk factors for GDM, including advanced maternal age, pre-pregnancy obesity and family history of diabetes, were strongly associated with an elevated GDM risk. Moreover, after the adjustment for the above-mentioned risk factors, a history of recurrent vulvovaginal candidiasis, residency in south China and a history of spontaneous abortion were significantly associated with an increased GDM risk; adjusted odds ratio (OR) [95% confidence interval (95% CI)] were 1.97 (1.39, 2.80), 1.84 (1.59-2.13), and 1.46 (1.12, 1.91), respectively.

Conclusions

In this large study of GDM in Chinese women, advanced maternal age, pre-pregnancy overweight or obesity and family history of diabetes were confirmed to be risk factors. In addition, a history of recurrent vulvovaginal candidiasis or spontaneous abortion and residency in south China appeared to be novel risk factors in this population.

语种英语
WOS记录号WOS:000271493900004
项目编号91000-242156028
资助机构national &prime ; 211&prime ; Project Peking University Evidence-Based Medicine Group ; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health
引用统计
被引频次:52[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54901
专题北京大学第一临床医学院
北京大学第三临床医学院_泌尿外科
北京大学临床肿瘤学院_乳腺癌预防治疗中心
作者单位1.W China Second Univ Hosp, Chengdu, Peoples R China
2.Tianjin Cent Hosp Obstet & Gynecol, Tianjin, Peoples R China
3.Peking Univ, Hosp 3, Beijing 100871, Peoples R China
4.Shanghai First Peoples Hosp, Shanghai, Peoples R China
5.Beijing Obstet & Gynecol Hosp, Beijing, Peoples R China
6.Nanjing Drum Tower Hosp, Nanjing, Peoples R China
7.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Div Epidemiol Stat & Prevent Res, NIH, Rockville, MD 20852 USA
8.Peking Univ, Hosp 1, Dept Obstet & Gynecol, Beijing 100871, Peoples R China
9.Zhejiang Univ, Sch Med, Womens Hosp, Hangzhou 310003, Zhejiang, Peoples R China
推荐引用方式
GB/T 7714
Yang, H.,Wei, Y.,Gao, X.,et al. Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China[J]. DIABETIC MEDICINE,2009,26(11):1099-1104.
APA Yang, H..,Wei, Y..,Gao, X..,Xu, X..,Fan, L..,...&China Natl GDM Survey Working Grp.(2009).Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China.DIABETIC MEDICINE,26(11),1099-1104.
MLA Yang, H.,et al."Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China".DIABETIC MEDICINE 26.11(2009):1099-1104.
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