|Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China|
|Yang, H.3; Wei, Y.3; Gao, X.3; Xu, X.2; Fan, L.4; He, J.5; Hu, Y.6; Liu, X.7; Chen, X.8; Yang, Z.9; Zhang, C.1; China Natl GDM Survey Working Grp|
|关键词||China Gestational Diabetes Pregnancy Risk Factor|
|WOS标题词||Science & Technology|
|类目[WOS]||Endocrinology & Metabolism|
|研究领域[WOS]||Endocrinology & Metabolism|
|关键词[WOS]||MATERNAL HYPERGLYCEMIA ; INCREASING PREVALENCE ; SPONTANEOUS-ABORTION ; ETHNICITY ; CITY|
To determine the incidence of gestational diabetes mellitus (GDM) in China and to further identify population specific risk factors for GDM.
Following a universal GDM screening recommendation, 16 286 pregnant women who underwent a 50-g glucose challenge test from 18 cities in China were followed up through pregnancy. GDM was confirmed by oral glucose tolerance test according to American Diabetes Association criteria.
The incidence of GDM was 4.3%. Previously reported risk factors for GDM, including advanced maternal age, pre-pregnancy obesity and family history of diabetes, were strongly associated with an elevated GDM risk. Moreover, after the adjustment for the above-mentioned risk factors, a history of recurrent vulvovaginal candidiasis, residency in south China and a history of spontaneous abortion were significantly associated with an increased GDM risk; adjusted odds ratio (OR) [95% confidence interval (95% CI)] were 1.97 (1.39, 2.80), 1.84 (1.59-2.13), and 1.46 (1.12, 1.91), respectively.
In this large study of GDM in Chinese women, advanced maternal age, pre-pregnancy overweight or obesity and family history of diabetes were confirmed to be risk factors. In addition, a history of recurrent vulvovaginal candidiasis or spontaneous abortion and residency in south China appeared to be novel risk factors in this population.
|资助机构||national &prime ; 211&prime ; Project Peking University Evidence-Based Medicine Group ; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health|
|作者单位||1.W China Second Univ Hosp, Chengdu, Peoples R China|
2.Tianjin Cent Hosp Obstet & Gynecol, Tianjin, Peoples R China
3.Peking Univ, Hosp 3, Beijing 100871, Peoples R China
4.Shanghai First Peoples Hosp, Shanghai, Peoples R China
5.Beijing Obstet & Gynecol Hosp, Beijing, Peoples R China
6.Nanjing Drum Tower Hosp, Nanjing, Peoples R China
7.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Div Epidemiol Stat & Prevent Res, NIH, Rockville, MD 20852 USA
8.Peking Univ, Hosp 1, Dept Obstet & Gynecol, Beijing 100871, Peoples R China
9.Zhejiang Univ, Sch Med, Womens Hosp, Hangzhou 310003, Zhejiang, Peoples R China
|Yang, H.,Wei, Y.,Gao, X.,et al. Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China[J]. DIABETIC MEDICINE,2009,26(11):1099-1104.|
|APA||Yang, H..,Wei, Y..,Gao, X..,Xu, X..,Fan, L..,...&China Natl GDM Survey Working Grp.(2009).Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China.DIABETIC MEDICINE,26(11),1099-1104.|
|MLA||Yang, H.,et al."Risk factors for gestational diabetes mellitus in Chinese women-a prospective study of 16 286 pregnant women in China".DIABETIC MEDICINE 26.11(2009):1099-1104.|