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学科主题: 精神卫生
题名:
Association of depression with adverse cardiovascular events after percutaneous coronary intervention
作者: Wang, Zhi Jian1; Guo, Min1,5; Si, Tian Mei2,3; Jiang, Ming Ming1,4; Liu, Si Meng1; Liu, Yu Yang1; Zhao, Ying Xin1; Shi, Dong Mei1; Zhou, Yu Jie1
关键词: coronary disease ; depression ; revascularization
刊名: CORONARY ARTERY DISEASE
发表日期: 2013-11-01
DOI: 10.1097/MCA.0b013e3283650234
卷: 24, 期:7, 页:589-595
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Peripheral Vascular Disease
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: ACUTE MYOCARDIAL-INFARCTION ; PSYCHOSOCIAL RISK-FACTORS ; HEART-DISEASE ; MAJOR DEPRESSION ; ARTERY-DISEASE ; SYMPTOMS ; MORTALITY ; PREDICTORS ; MORBIDITY ; DISORDER
英文摘要:

ObjectiveThe aim of this study was to investigate the impact of depression on the clinical outcomes of patients with coronary artery disease undergoing percutaneous coronary intervention (PCI).MethodsA total of 400 patients treated with PCI were assessed using the Mini-International Neuropsychiatric Interview 1 day before and 2 weeks after the procedure. All patients were followed up for 3 years after the procedure. The primary endpoint was a major adverse cardiovascular event (MACE) including mortality, nonfatal myocardial infarction, or repeat revascularization.ResultsDepression was present in 38.5% (n=154) of patients after the procedure, which was significantly higher than that before the procedure (25.5%, P<0.001). Patients with postprocedure depression had a higher rate of MACE (27.3 vs. 13.0%, P<0.001), mortality (5.8 vs. 2.0%, P=0.044), and repeat revascularization (13.0 vs. 6.5%, P=0.027) compared with patients without depression during the 3 years of follow-up. After adjustment for other factors that affect cardiovascular outcomes, postprocedure depression was seen to be an independent predictor of 3-year MACE [hazard ratio: 2.51, 95% confidence interval (CI): 1.57-4.02, P<0.001], mortality (3.60, 95% CI: 1.16-11.22, P=0.027), and repeat revascularization (hazard ratio: 2.22, 95% CI: 1.09-4.51, P=0.029).ConclusionDepression is common among patients treated with PCI. Postprocedure depression is an independent predictor of 3-year MACE, mortality, and repeat revascularization.

语种: 英语
所属项目编号: Z07050700690711
项目资助者: Research on Application and Development of the Characteristics of the Capital, Beijing, PR China
WOS记录号: WOS:000325427900010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54911
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing 100029, Peoples R China
2.Peking Univ, Dept Clin Psychopharmacol, Inst Mental Hlth, Beijing 100871, Peoples R China
3.Minist Hlth, Key Lab Mental Hlth, Beijing, Peoples R China
4.Zhongguancun Hosp, Beijing, Peoples R China
5.Jilin Med Coll, Affiliated Hosp, Changchun, Jilin, Peoples R China

Recommended Citation:
Wang, Zhi Jian,Guo, Min,Si, Tian Mei,et al. Association of depression with adverse cardiovascular events after percutaneous coronary intervention[J]. CORONARY ARTERY DISEASE,2013,24(7):589-595.
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