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Association of depression with adverse cardiovascular events after percutaneous coronary intervention
Wang, Zhi Jian1; Guo, Min1,5; Si, Tian Mei2,3; Jiang, Ming Ming1,4; Liu, Si Meng1; Liu, Yu Yang1; Zhao, Ying Xin1; Shi, Dong Mei1; Zhou, Yu Jie1
关键词Coronary Disease Depression Revascularization
刊名CORONARY ARTERY DISEASE
2013-11-01
DOI10.1097/MCA.0b013e3283650234
24期:7页:589-595
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Peripheral Vascular Disease
研究领域[WOS]Cardiovascular System & Cardiology
关键词[WOS]ACUTE MYOCARDIAL-INFARCTION ; PSYCHOSOCIAL RISK-FACTORS ; HEART-DISEASE ; MAJOR DEPRESSION ; ARTERY-DISEASE ; SYMPTOMS ; MORTALITY ; PREDICTORS ; MORBIDITY ; DISORDER
英文摘要

ObjectiveThe aim of this study was to investigate the impact of depression on the clinical outcomes of patients with coronary artery disease undergoing percutaneous coronary intervention (PCI).MethodsA total of 400 patients treated with PCI were assessed using the Mini-International Neuropsychiatric Interview 1 day before and 2 weeks after the procedure. All patients were followed up for 3 years after the procedure. The primary endpoint was a major adverse cardiovascular event (MACE) including mortality, nonfatal myocardial infarction, or repeat revascularization.ResultsDepression was present in 38.5% (n=154) of patients after the procedure, which was significantly higher than that before the procedure (25.5%, P<0.001). Patients with postprocedure depression had a higher rate of MACE (27.3 vs. 13.0%, P<0.001), mortality (5.8 vs. 2.0%, P=0.044), and repeat revascularization (13.0 vs. 6.5%, P=0.027) compared with patients without depression during the 3 years of follow-up. After adjustment for other factors that affect cardiovascular outcomes, postprocedure depression was seen to be an independent predictor of 3-year MACE [hazard ratio: 2.51, 95% confidence interval (CI): 1.57-4.02, P<0.001], mortality (3.60, 95% CI: 1.16-11.22, P=0.027), and repeat revascularization (hazard ratio: 2.22, 95% CI: 1.09-4.51, P=0.029).ConclusionDepression is common among patients treated with PCI. Postprocedure depression is an independent predictor of 3-year MACE, mortality, and repeat revascularization.

语种英语
WOS记录号WOS:000325427900010
项目编号Z07050700690711
资助机构Research on Application and Development of the Characteristics of the Capital, Beijing, PR China
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54911
专题北京大学精神卫生研究所
作者单位1.Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing 100029, Peoples R China
2.Peking Univ, Dept Clin Psychopharmacol, Inst Mental Hlth, Beijing 100871, Peoples R China
3.Minist Hlth, Key Lab Mental Hlth, Beijing, Peoples R China
4.Zhongguancun Hosp, Beijing, Peoples R China
5.Jilin Med Coll, Affiliated Hosp, Changchun, Jilin, Peoples R China
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GB/T 7714
Wang, Zhi Jian,Guo, Min,Si, Tian Mei,et al. Association of depression with adverse cardiovascular events after percutaneous coronary intervention[J]. CORONARY ARTERY DISEASE,2013,24(7):589-595.
APA Wang, Zhi Jian.,Guo, Min.,Si, Tian Mei.,Jiang, Ming Ming.,Liu, Si Meng.,...&Zhou, Yu Jie.(2013).Association of depression with adverse cardiovascular events after percutaneous coronary intervention.CORONARY ARTERY DISEASE,24(7),589-595.
MLA Wang, Zhi Jian,et al."Association of depression with adverse cardiovascular events after percutaneous coronary intervention".CORONARY ARTERY DISEASE 24.7(2013):589-595.
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