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Cytotoxic diterpenoids from the bark of Pseudolarix kaempferi and their structure-activity relationships
Liu, Peng; Guo, Hongzhu; Wang, Weixing; Zhang, Jie; Li, Na; Han, Jian; Zhou, Jianping; Hu, Yuchi; Zhang, Tong; Liu, Zhenming; Guo, Dean
刊名JOURNAL OF NATURAL PRODUCTS
2007-04-01
DOI10.1021/np060439q
70期:4页:533-537
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]ACID-B ; ACETATES
英文摘要

Four new diterpenoids, 11S-deacetylpseudolaric acid A (2), deacetylpseudolaric acid A O-beta-D-glucopyranoside (3), deacetylpseudolaric acid A 2,3-dihydroxypropyl ester (4), and deacetylpseudolaric acid B 2,3-dihydroxypropyl ester (5), and nine known diterpenoids were isolated from the bark of Pseudolarix kaempferi. Their structures were determined on the basis of chemical and spectroscopic analyses. In addition, their in vitro cytotoxic activities against three human cancer cell lines and their structure-activity relationships were evaluated.

语种英语
WOS记录号WOS:000246007200007
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54934
专题北京大学药学院
作者单位1.Beijing Inst Drug Control, Beijing 100035, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, Div Pharmacognost Biotechnol, Beijing 100083, Peoples R China
3.Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Liu, Peng,Guo, Hongzhu,Wang, Weixing,et al. Cytotoxic diterpenoids from the bark of Pseudolarix kaempferi and their structure-activity relationships[J]. JOURNAL OF NATURAL PRODUCTS,2007,70(4):533-537.
APA Liu, Peng.,Guo, Hongzhu.,Wang, Weixing.,Zhang, Jie.,Li, Na.,...&Guo, Dean.(2007).Cytotoxic diterpenoids from the bark of Pseudolarix kaempferi and their structure-activity relationships.JOURNAL OF NATURAL PRODUCTS,70(4),533-537.
MLA Liu, Peng,et al."Cytotoxic diterpenoids from the bark of Pseudolarix kaempferi and their structure-activity relationships".JOURNAL OF NATURAL PRODUCTS 70.4(2007):533-537.
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