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学科主题: 精神卫生
题名:
Atypical features and treatment choices in bipolar disorders: a result of the National Bipolar Mania Pathway Survey in China
作者: Peng, Daihui1; Shen, Ting1; Byrne, Linda2; Zhang, Chen1; Huang, Yueqi1; Yu, Xin3; Zhao, Jingping4; McCabe, Marita2; Mellor, David2; Fang, Yiru1
关键词: atypical features ; bipolar ; treatment ; antidepressant
刊名: NEUROSCIENCE BULLETIN
发表日期: 2015-02-01
DOI: 10.1007/s12264-014-1487-3
卷: 31, 期:1, 页:22-30
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Neurosciences
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: II-DISORDER ; DEPRESSIVE-ILLNESS ; SPECTRUM DISORDER ; MENTAL-DISORDERS ; PRIVATE-PRACTICE ; PREVALENCE ; COMORBIDITY ; POPULATION ; DISABILITY ; DIAGNOSIS
英文摘要:

In this study, we examined the point prevalence rate of atypical features in bipolar disorder, and estimated the potential impact of these features on treatment practices in China. Using the atypical features criteria of the Diagnostic and Statistical Manual of the American Psychiatric Association (DSM-IV), we documented the atypical symptoms in 3 906 consecutive participants with bipolar disorder enrolled at 26 psychiatric services across China. We further assessed the association between atypical features and the treatment approaches, including the prescription of antidepressants. The overall point prevalence rate of atypical features was 9.1% among patients with various bipolar disorder subtypes. When the definition was broadened to include atypical features B, the overall rate increased to 11.8%. Interestingly, among patients with the mixed state and remission subtypes, there was a significant difference in the rates of antidepressant medication usage between patients who met and those who did not meet the criteria for atypical features B. These findings indicate a trend of using antidepressants for these two types of patients with atypical features. Further, for both mixed state and remission patients, treatment approaches were related to atypical features B. Our findings provide evidence to assist clinicians to readily recognize atypical features in bipolar subtypes and can propose treatments based on these diagnoses.

语种: 英语
所属项目编号: 11XJ21006 ; YG2012MS11 ; 134119a6200 ; GWHW201208 ; 2012BAI01B04 ; 91232719 ; 2011-873
项目资助者: Shanghai Jiao Tong University ; Science and Technology Commission of Shanghai Municipality, China ; Overseas Talent Project of the Shanghai Health Bureau, China ; "12th Five-year Plan" of the National Key Technologies R&amp ; D Program, China ; National Natural Science Foundation of China ; National Key Clinical Disciplines at the Shanghai Mental Health Center, China (OMA-MH)
WOS记录号: WOS:000349316700004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54963
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Peking Univ, Inst Mental Hlth, Beijing 100191, Peoples R China
2.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Shanghai Clin Ctr Mental Disorder,Dept Psychiat,D, Shanghai 200030, Peoples R China
3.Deakin Univ, Sch Psychol Burwood Campus, Melbourne, Vic, Australia
4.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha 410011, Hunan, Peoples R China

Recommended Citation:
Peng, Daihui,Shen, Ting,Byrne, Linda,et al. Atypical features and treatment choices in bipolar disorders: a result of the National Bipolar Mania Pathway Survey in China[J]. NEUROSCIENCE BULLETIN,2015,31(1):22-30.
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