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学科主题: 精神卫生
题名:
The protocols for the 10/66 dementia research group population-based research programme
作者: Prince, Martin; Ferri, Cleusa P.; Acosta, Daisy; Albanese, Emiliano; Arizaga, Raul; Dewey, Michael; Gavrilova, Svetlana I.; Guerra, Mariella; Huang, Yueqin; Jacob, K. S.; Krishnamoorthy, E. S.; McKeigue, Paul; Rodriguez, Juan Llibre; Salas, Aquiles; Sosa, Ana Luisa; Sousa, Renata M. M.; Stewart, Robert; Uwakwe, Richard
刊名: BMC PUBLIC HEALTH
发表日期: 2007-07-20
DOI: 10.1186/1471-2458-7-165
卷: 7
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Public, Environmental & Occupational Health
研究领域[WOS]: Public, Environmental & Occupational Health
关键词[WOS]: NORTHERN MANHATTAN STROKE ; VASCULAR RISK-FACTORS ; QUALITY-OF-LIFE ; ALZHEIMERS-DISEASE ; DEVELOPING-COUNTRIES ; AFRICAN-AMERICANS ; APOLIPOPROTEIN-E ; CARDIOVASCULAR-DISEASE ; DIAGNOSTIC-CRITERIA ; ELDERLY POPULATION
英文摘要:

Background: Latin America, China and India are experiencing unprecedentedly rapid demographic ageing with an increasing number of people with dementia. The 10/ 66 Dementia Research Group′s title refers to the 66% of people with dementia that live in developing countries and the less than one tenth of population-based research carried out in those settings. This paper describes the protocols for the 10/ 66 population-based and intervention studies that aim to redress this imbalance.

Methods/ design: Cross-sectional comprehensive one phase surveys have been conducted of all residents aged 65 and over of geographically defined catchment areas in ten low and middle income countries (India, China, Nigeria, Cuba, Dominican Republic, Brazil, Venezuela, Mexico, Peru and Argentina), with a sample size of between 1000 and 3000 (generally 2000). Each of the studies uses the same core minimum data set with cross-culturally validated assessments (dementia diagnosis and subtypes, mental disorders, physical health, anthropometry, demographics, extensive non communicable disease risk factor questionnaires, disability/ functioning, health service utilisation, care arrangements and caregiver strain). Nested within the population based studies is a randomised controlled trial of a caregiver intervention for people with dementia and their families (ISRCTN41039907; ISRCTN41062011; ISRCTN95135433;ISRCTN66355402; ISRCTN93378627; ISRCTN94921815). A follow up of 2.5 to 3.5 years will be conducted in 7 countries (China, Cuba, Dominican Republic, Venezuela, Mexico, Peru and Argentina) to assess risk factors for incident dementia, stroke and all cause and cause-specific mortality; verbal autopsy will be used to identify causes of death.

Discussion: The 10/ 66 DRG baseline population-based studies are nearly complete. The incidence phase will be completed in 2009. All investigators are committed to establish an anonymised file sharing archive with monitored public access. Our aim is to create an evidence base to empower advocacy, raise awareness about dementia, and ensure that the health and social care needs of older people are anticipated and met.

语种: 英语
WOS记录号: WOS:000249302300001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/54965
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Kings Coll London, Hlth Serv & Populat Res Dept, Epidemiol Sect, London SE5 8AF, England
2.Univ Nacl Pedro Henriquez Urena, Geriatr Sect, Dept Internal Med, Santo Domingo, Dominican Rep
3.Neuraxis Inst, Neurol Fdn, Behav & Cognit Neurol Unit, Buenos Aires, DF, Argentina
4.Russian Acad Med Sci, Mental Hlth Res Ctr, Moscow, Russia
5.Natl Inst Mental Hlth Honorio Delgado Hideyo Nogu, Psychogeriatr Unit, Lima, Peru
6.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
7.Christian Med Coll & Hosp, Vellore, Tamil Nadu, India
8.Srinivasan Ctr Clin Neurosci, Inst Neurol Sci, Voluntary Hlth Serv, Madras, Tamil Nadu, India
9.Univ Coll Dublin, Genet & Epidemiol Dept Conway Inst, Dublin 2, Ireland
10.Med Univ Havana, Fac Med Finley Albarran, Havana, Cuba
11.Cent Univ Venezuela, Fac Med, Hop Univ Caracas, Dept Med, Caracas, Venezuela
12.Natl Inst Neurol & Neurosurg Mexico, Cognit & Behav Unit, Mexico City, DF, Mexico
13.Nnamdi Azikiwe Univ Teaching Hosp, Dept Mental Hlth, Nnewi, Anambra State, Nigeria

Recommended Citation:
Prince, Martin,Ferri, Cleusa P.,Acosta, Daisy,et al. The protocols for the 10/66 dementia research group population-based research programme[J]. BMC PUBLIC HEALTH,2007,7.
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