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学科主题口腔医学
Giant cell granuloma of the temporal bone - A case report with immunohistochemical, enzyme histochemical, and in vitro studies
Tian, XF; Li, TJ; Yu, SF
刊名ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
2003-09-01
127期:9页:1217-1220
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medical Laboratory Technology ; Medicine, Research & Experimental ; Pathology
研究领域[WOS]Medical Laboratory Technology ; Research & Experimental Medicine ; Pathology
关键词[WOS]REPARATIVE GRANULOMA ; LESIONS
英文摘要

A case of giant cell granuloma (GCG) that occurred in the right temporal bone is reported. The lesion showed histologic features identical to GCG. The multinuclear giant cells (MGCs) in the lesion showed strong reactivity with CD68, but patchy staining for myeloid/histiocyte antigen, alpha-1-antitrypsin, alpha-1-antichymotrypsine, and lysozyme. Activity of tartrate-resistant acid phosphatase was also consistently detected in the MGCs. Some of the mononuclear cells of the lesion exhibited similar immunocytochemical and histochemical reactivity as the MGCs. Ki-67 staining, however, was only detected in the mononuclear cells. The MGCs isolated from the lesion presented characteristic morphology of osteoclasts and possessed the ability to excavate bone in vitro. Thus, the MGCs in GCG appeared to express both macrophage- and osteoclast-associated phenotypes. The mononuclear cells were the major proliferative elements in the lesion and a subpopulation of these cells may represent precursors of the MGCs.

语种英语
WOS记录号WOS:000185240300030
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/54969
专题北京大学口腔医学院_口腔病理科
作者单位Peking Univ, Sch Stomatol, Dept Oral Pathol, Beijing 100081, Peoples R China
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GB/T 7714
Tian, XF,Li, TJ,Yu, SF. Giant cell granuloma of the temporal bone - A case report with immunohistochemical, enzyme histochemical, and in vitro studies[J]. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE,2003,127(9):1217-1220.
APA Tian, XF,Li, TJ,&Yu, SF.(2003).Giant cell granuloma of the temporal bone - A case report with immunohistochemical, enzyme histochemical, and in vitro studies.ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE,127(9),1217-1220.
MLA Tian, XF,et al."Giant cell granuloma of the temporal bone - A case report with immunohistochemical, enzyme histochemical, and in vitro studies".ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE 127.9(2003):1217-1220.
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