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Allo-hematopoietic stem cell transplantation is a potential treatment for a patient with a combined disorder of hereditary spherocytosis
Zhang Xiao-hui; Fu Hai-xia; Xu Lan-ping; Liu Dai-hong; Chen Huan; Han Wei; Chen Yu-hong; Wang Feng-rong; Wang Jing-zhi; Wang Yu; Zhao Ting; Liu Kai-yan; Huang Xiao-jun
关键词Hereditary Spherocytosis Allogeneic Stem Cell Transplantation Chronic Myelogenous Leukemia
刊名CHINESE MEDICAL JOURNAL
2012-03-05
DOI10.3760/cma.j.issn.0366-6999.2012.05.039
125期:5页:947-950
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
资助者National Natural Science Foundation of China ; Science Foundation of Beijing City in China ; National Natural Science Foundation of China ; Science Foundation of Beijing City in China
研究领域[WOS]General & Internal Medicine
关键词[WOS]BONE-MARROW-TRANSPLANTATION ; LEUKEMIA ; MICE ; THROMBOSIS
英文摘要

Both human hereditary spherocytosis (HS) and chronic myelogenous leukemia (CML) are life threatening. Herein we have reported the case of a woman with a combined disorder of HS and CML who underwent the matched sibling allogeneic stem cell transplantation. The complete donor erythroid cells were obtained. The red blood cell counts significantly improved throughout life comparing with pre-hematopoietic stem cell transplantation (HSCT). Reticulocyte counts normalized, and BCR-ABL was cleared away. The total bilirubin level was also corrected in this recipient. Our case is a rare example with a combined disorder of HS and CML following allogeneic stem cell transplantation. HS was not a contraindication for patient in the matched sibling transplant setting. Chin Med J 2012;125(5):947-950

语种英语
所属项目编号30770911 ; 81070449 ; 7112139
资助者National Natural Science Foundation of China ; Science Foundation of Beijing City in China ; National Natural Science Foundation of China ; Science Foundation of Beijing City in China
WOS记录号WOS:000301755200041
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55031
专题北京大学第二临床医学院_血液科
作者单位Peking Univ, Inst Hematol, Peoples Hosp, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Zhang Xiao-hui,Fu Hai-xia,Xu Lan-ping,et al. Allo-hematopoietic stem cell transplantation is a potential treatment for a patient with a combined disorder of hereditary spherocytosis[J]. CHINESE MEDICAL JOURNAL,2012,125(5):947-950.
APA Zhang Xiao-hui.,Fu Hai-xia.,Xu Lan-ping.,Liu Dai-hong.,Chen Huan.,...&Huang Xiao-jun.(2012).Allo-hematopoietic stem cell transplantation is a potential treatment for a patient with a combined disorder of hereditary spherocytosis.CHINESE MEDICAL JOURNAL,125(5),947-950.
MLA Zhang Xiao-hui,et al."Allo-hematopoietic stem cell transplantation is a potential treatment for a patient with a combined disorder of hereditary spherocytosis".CHINESE MEDICAL JOURNAL 125.5(2012):947-950.
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