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IR@PKUHSC  > 北京大学第二临床医学院  > 血液科  > 期刊论文
学科主题: 临床医学
题名:
Allo-hematopoietic stem cell transplantation is a potential treatment for a patient with a combined disorder of hereditary spherocytosis
作者: Zhang Xiao-hui; Fu Hai-xia; Xu Lan-ping; Liu Dai-hong; Chen Huan; Han Wei; Chen Yu-hong; Wang Feng-rong; Wang Jing-zhi; Wang Yu; Zhao Ting; Liu Kai-yan; Huang Xiao-jun
关键词: hereditary spherocytosis ; allogeneic stem cell transplantation ; chronic myelogenous leukemia
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2012-03-05
DOI: 10.3760/cma.j.issn.0366-6999.2012.05.039
卷: 125, 期:5, 页:947-950
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: BONE-MARROW-TRANSPLANTATION ; LEUKEMIA ; MICE ; THROMBOSIS
英文摘要:

Both human hereditary spherocytosis (HS) and chronic myelogenous leukemia (CML) are life threatening. Herein we have reported the case of a woman with a combined disorder of HS and CML who underwent the matched sibling allogeneic stem cell transplantation. The complete donor erythroid cells were obtained. The red blood cell counts significantly improved throughout life comparing with pre-hematopoietic stem cell transplantation (HSCT). Reticulocyte counts normalized, and BCR-ABL was cleared away. The total bilirubin level was also corrected in this recipient. Our case is a rare example with a combined disorder of HS and CML following allogeneic stem cell transplantation. HS was not a contraindication for patient in the matched sibling transplant setting. Chin Med J 2012;125(5):947-950

语种: 英语
所属项目编号: 30770911 ; 81070449 ; 7112139
项目资助者: National Natural Science Foundation of China ; Science Foundation of Beijing City in China
WOS记录号: WOS:000301755200041
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55031
Appears in Collections:北京大学第二临床医学院_血液科_期刊论文

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作者单位: Peking Univ, Inst Hematol, Peoples Hosp, Beijing 100044, Peoples R China

Recommended Citation:
Zhang Xiao-hui,Fu Hai-xia,Xu Lan-ping,et al. Allo-hematopoietic stem cell transplantation is a potential treatment for a patient with a combined disorder of hereditary spherocytosis[J]. CHINESE MEDICAL JOURNAL,2012,125(5):947-950.
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