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学科主题: 药学
题名:
Microbial transformation of ginsenoside Rb-1 by Rhizopus stolonifer and Curvularia lunata
作者: Dong, AL; Ye, M; Guo, HZ; Zheng, JH; Guo, D
关键词: biotransformation ; Curvularia lunata ; ginsenoside ; Rhizopus stolonifer
刊名: BIOTECHNOLOGY LETTERS
发表日期: 2003-02-01
卷: 25, 期:4, 页:339-344
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology
研究领域[WOS]: Biotechnology & Applied Microbiology
关键词[WOS]: INTESTINAL BACTERIA ; TRITERPENE SAPONINS
英文摘要:

Of 49 microbial strains screened for their capabilities to transform ginsenoside Rb-1, Rhizopus stolonifer and Curvularia lunata produced four key metabolites: 3-O-[beta-D-glucopyranosyl-(1,2)-beta-D-glucopyranosyl]- 20-O-[beta-D-glucopyranosyl]-3beta,12beta, 20(S)-trihydroxydammar-24-ene (1), 3-O-[beta-D-glucopyranosyl-(1,2)-beta-D-glucopyranosyl]-20-O-[beta-D-glucopyranosyl]-3beta,12beta, 20(S)-trihydroxydammar-24-ol (2), 3-O-[beta-D- glucopyranosyl-(1,2)-beta-D-glucopyranosyl]-3beta,12beta, 20(S)-trihydroxydammar-24-ene(3), and 3-O-beta-D-glucopyranosyl- 3beta,12beta,20(S)-trihydroxydammar-24-ene(4), identified by TOF-MS, H-1- and C-13-NMR spectral data. Metabolites 1, 3 and 4 were from the incubation with R. stolonifer, and 1 and 2 from the incubation with C. lunata. Compound 2 was identified as a new compound.

语种: 英语
WOS记录号: WOS:000181009800011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55062
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

Recommended Citation:
Dong, AL,Ye, M,Guo, HZ,et al. Microbial transformation of ginsenoside Rb-1 by Rhizopus stolonifer and Curvularia lunata[J]. BIOTECHNOLOGY LETTERS,2003,25(4):339-344.
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