北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第二临床医学院  > 心血管内科  > 期刊论文
学科主题: 临床医学
题名:
Impact of Anemia and Dual Antiplatelet Therapy on Mortality in Patients Undergoing Percutaneous Coronary Intervention with Drug-Eluting Stents
作者: Wang, Huili1,2; Yang, Yuan3; Ma, Lufeng1; Wang, Xian4; Zhang, Jun5; Fu, Jinguo5; Zhang, Shouyan6; Zhang, Ling1; Hu, Dayi7; Ding, Rongjing7
刊名: SCIENTIFIC REPORTS
发表日期: 2015-11-25
DOI: 10.1038/srep17213
卷: 5
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: ASSOCIATION TASK-FORCE ; BARE-METAL STENTS ; MYOCARDIAL REVASCULARIZATION ; PRACTICE GUIDELINES ; ARTERY-DISEASE ; RISK ; TERM ; METAANALYSIS ; HEMOGLOBIN ; THROMBOSIS
英文摘要:

The objective was to assess the impact of baseline anemia on all-cause mortality and whether 12-month dual antiplatelet therapy (DAPT) affects 1-year mortality linked to anemia in patients after percutaneous coronary intervention (PCI) with drug-eluting stents (DES). 4109 enrolled patients divided into three groups based on their pre-procedural hemoglobin (Hb) level: Hb < 100 mg/L represented moderate-severe anemia; 100 mg/L <= Hb < 120 mg/L for women and 100 mg/L <= Hb < 130 mg/L for men represented mild anemia; Hb >= 120 mg/L for women and Hb >= 130 mg/L for men represented no anemia. DAPT medications were prescribed when patients were discharged. There were significant differences in 30-day and 1-year mortality between moderate-severe anemia and no anemia patients (HR 8.05, 95% CI 1.46 to 44.33, P = 0.017; HR 3.93, 95% CI 1.11 to 13.98, P = 0.034), and in long-term mortality between anemia and no anemia groups (HR 1.82, 95% CI 1.17 to 2.83, P = 0.008 for mild anemia; HR 3.19,95% CI 1.29 to 7.86, P = 0.012 for moderate-severe anemia). There was not significant interaction between 12-month DAPT and anemia on mortality in anemic patients (P for interaction >0.05). Anemia shows association with increased all-cause mortality in patients undergoing PCI. Twelve-month DAPT does not show synergy with anemia to increase the risk of all-cause 1-year mortality in anemic patients after PCI.

语种: 英语
WOS记录号: WOS:000365335900001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55127
Appears in Collections:北京大学第二临床医学院_心血管内科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Capital Med Univ, Sch Publ Hlth, Beijing, Peoples R China
2.Capital Med Univ, Sch Gen Practice & Continuing Educ, Beijing, Peoples R China
3.Chongqing Med Univ, Affiliated Hosp 1, Dept Cardiol, Chongqing, Peoples R China
4.Beijing Univ, Chinese Med Dongzhimen Hosp, Dept Cardiol, Beijing 100871, Peoples R China
5.Cangzhou Cent Hosp, Dept Cardiol, Cangzhou, Hebei Province, Peoples R China
6.Zhengzhou Univ, Luoyang Cent Hosp, Dept Cardiol, Luoyang, Henan Province, Peoples R China
7.Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100871, Peoples R China

Recommended Citation:
Wang, Huili,Yang, Yuan,Ma, Lufeng,et al. Impact of Anemia and Dual Antiplatelet Therapy on Mortality in Patients Undergoing Percutaneous Coronary Intervention with Drug-Eluting Stents[J]. SCIENTIFIC REPORTS,2015,5.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Wang, Huili]'s Articles
[Yang, Yuan]'s Articles
[Ma, Lufeng]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Wang, Huili]‘s Articles
[Yang, Yuan]‘s Articles
[Ma, Lufeng]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace