IR@PKUHSC  > 北京大学第一临床医学院  > 临床药理研究所
学科主题临床医学
Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives
Xu, Peng1; Liu, Lu1; He, Wei1; Li, Yun2; Liu, Jian2; Lei, Ping-Sheng1
关键词Macrolide Acylide Antibacterial Activity Resistant Strains
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2009
DOI10.1080/10286020903176461
11期:10页:880-897
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]MACROLIDE ANTIBIOTICS ; RESISTANT ; ACYLIDES ; INHIBITORS ; PATHOGENS ; ANALOGS ; POTENT
英文摘要

A novel series of acylide derivatives have been synthesized which exhibit in vitro potency against key respiratory pathogens. Modification of position 3 was accomplished by replacing different 3-O-substituted acyl groups in the macrolide core via a facile procedure. Compounds 7a-7i were eventually yielded by the conjunction of diverse hetero-aryl side chains with the 11-N,12-O-carbamate sub-structure.

语种英语
WOS记录号WOS:000271181100006
项目编号30572275 ; 7062047
资助机构National Natural Science Foundation of China ; Natural Science Foundation of Beijing
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55189
专题北京大学第一临床医学院_临床药理研究所
北京大学口腔医学院_口腔预防保健科
作者单位1.Chinese Acad Med Sci, Inst Mat Med, Peking Union Med Coll, Beijing 100050, Peoples R China
2.Peking Univ, Inst Clin Pharmacol, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Xu, Peng,Liu, Lu,He, Wei,et al. Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2009,11(10):880-897.
APA Xu, Peng,Liu, Lu,He, Wei,Li, Yun,Liu, Jian,&Lei, Ping-Sheng.(2009).Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,11(10),880-897.
MLA Xu, Peng,et al."Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 11.10(2009):880-897.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Xu, Peng]的文章
[Liu, Lu]的文章
[He, Wei]的文章
百度学术
百度学术中相似的文章
[Xu, Peng]的文章
[Liu, Lu]的文章
[He, Wei]的文章
必应学术
必应学术中相似的文章
[Xu, Peng]的文章
[Liu, Lu]的文章
[He, Wei]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。