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IR@PKUHSC  > 北京大学第二临床医学院  > 骨肿瘤科  > 期刊论文
学科主题: 临床医学
题名:
Postoperative recurrence of desmoid tumors: clinical and pathological perspectives
作者: Wang, Yi-fei1; Guo, Wei1; Sun, Kun-kun2; Yang, Rong-li1; Tang, Xiao-dong1; Ji, Tao1; Tang, Shun1
关键词: Histopathology ; Immunohistochemistry ; Tumor resection
刊名: WORLD JOURNAL OF SURGICAL ONCOLOGY
发表日期: 2015-02-07
DOI: 10.1186/s12957-015-0450-8
卷: 13
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Surgery
研究领域[WOS]: Oncology ; Surgery
关键词[WOS]: AGGRESSIVE FIBROMATOSIS ; RADIATION-THERAPY ; TAMOXIFEN
英文摘要:

Background: The clinical features and the pathological changes of desmoid tumors were studied to point out the key factors affecting the recurrence.

Methods: The clinical data and specimens of 56 patients who underwent desmoid tumor resection from 2003 to 2008 were reviewed. Possible clinical factors related to the postoperative recurrence were analyzed statistically. The specimens round the lesions were studied histopathologically.

Results: The overall recurrence rate was 39.3%. The postoperative recurrence rate of the patients with negative surgical margins and no tumor invasion of the major vessels and nerves was low (P < 0.05). However, the desmoid tumors could destroy the cortical bone and invade the medullary cavity.

Conclusions: Desmoid tumors were pathologically benign, which could extensively invade tissues around the lesions. The invasion of major vessels and nerves and quality of surgical margins are the key factors for the high postoperative recurrence rate.

语种: 英语
WOS记录号: WOS:000349595200001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55205
Appears in Collections:北京大学第二临床医学院_骨肿瘤科_期刊论文

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作者单位: 1.Peking Univ Peoples Hosp, Musculoskeletal Tumor Ctr, Beijing 100044, Peoples R China
2.Peking Univ Peoples Hosp, Dept Pathol, Beijing 100044, Peoples R China

Recommended Citation:
Wang, Yi-fei,Guo, Wei,Sun, Kun-kun,et al. Postoperative recurrence of desmoid tumors: clinical and pathological perspectives[J]. WORLD JOURNAL OF SURGICAL ONCOLOGY,2015,13.
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