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A new 1, 10-secoguaianolide from the aerial parts of Artemisia anomala
Zan Ke1; Chen Xiao-Qing2; Tu Peng-Fei1
关键词Artemisia Anomala Chemical Constituents Structure Elucidation 1 10-secoguaianolides
刊名CHINESE JOURNAL OF NATURAL MEDICINES
2012-09-01
DOI10.3724/SP.J.1009.2012.00358
10期:5页:358-362
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine ; Pharmacology & Pharmacy
研究领域[WOS]Integrative & Complementary Medicine ; Pharmacology & Pharmacy
关键词[WOS]SESQUITERPENE LACTONES ; DERIVATIVES
英文摘要

AIM: To study chemical constituents of the aerial parts of Artemisia anomala (Asteraceae). METHODS: The constituents were isolated with silica gel, ODS column chromatography and semi-preparative HPLC, and their structures were elucidated on the basis of physical characteristics and spectral data. RESULTS: Eight compounds were obtained, and their structures were identified as 3 beta-ethoxytanapartholide (1), (4S*, 5S*)-dihydro-5-[( 1R*, 2S*)-2-hydroxy-2-methyl-5-oxo-3-cyclopenten-1-yl]-3-methylene-4-(3-oxobutyl)-2(3H)-furanone (2), ligucyperonol (3), cyperusol C (4), santamarin (5), 1 alpha, 2 alpha, 3 alpha, 4 alpha, 10 alpha -pentahydroxyguaia-11(13)-ene-12, 6 alpha-olide (6), balanophonin (7), methyl 3-(2′-hydroxy-4′-methoxyphenyl) propanoate (8). CONCLUSION: Compound 1 was a new artifact, 4 and 8 were isolated from the genus Artemisia for the first time, and compounds 2-3, 5-7 were isolated from this plant for the first time.

语种英语
WOS记录号WOS:000309035800007
项目编号30973629 ; 20110490251 ; K20120213 ; 11ZYH08
资助机构National Natural Science Foundation of China ; China Post-doctoral Science Foundation ; Foundation of State Key Laboratory of Natural and Biomimetic Drugs in Peking University ; Capital TCM &amp ; Nursing Foundation
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55236
专题北京大学药学院
北京大学药学院_天然药物学系
作者单位1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Capital Med Univ, Sch Tradit Chinese Med, Beijing 100069, Peoples R China
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GB/T 7714
Zan Ke,Chen Xiao-Qing,Tu Peng-Fei. A new 1, 10-secoguaianolide from the aerial parts of Artemisia anomala[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2012,10(5):358-362.
APA Zan Ke,Chen Xiao-Qing,&Tu Peng-Fei.(2012).A new 1, 10-secoguaianolide from the aerial parts of Artemisia anomala.CHINESE JOURNAL OF NATURAL MEDICINES,10(5),358-362.
MLA Zan Ke,et al."A new 1, 10-secoguaianolide from the aerial parts of Artemisia anomala".CHINESE JOURNAL OF NATURAL MEDICINES 10.5(2012):358-362.
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