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An efficient organocatalytic enantioselective Michael addition of aryl methyl ketones with 2-furanones: highly functionalized chiral 3,4-substituted lactones
Wang, Wei; Wang, Junfeng; Zhou, Shuo; Sun, Qi; Ge, Zemei; Wang, Xin; Li, Runtao
刊名CHEMICAL COMMUNICATIONS
2013
DOI10.1039/c2cc35488h
49期:13页:1333-1335
收录类别SCI ; IC ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]ALDOL REACTION ; CATALYSIS ; DERIVATIVES ; ACID
英文摘要

The efficient asymmetric Michael addition reactions of aryl methyl ketones with 2-furanones were catalyzed by a simple and commercially available chiral 1,2-diphenyl-1,2-ethanediamine and p-TSA center dot H2O as cocatalyst with good yields (up to 95%) and excellent enantioselectivities (up to >99% ee). A bi-functional catalytic mechanism for the reaction was proposed.

语种英语
WOS记录号WOS:000313663900026
项目编号20972005
资助机构National Natural Science Foundation of China
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55347
专题北京大学药学院
北京大学药学院_化学生物学系
作者单位Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Wang, Wei,Wang, Junfeng,Zhou, Shuo,et al. An efficient organocatalytic enantioselective Michael addition of aryl methyl ketones with 2-furanones: highly functionalized chiral 3,4-substituted lactones[J]. CHEMICAL COMMUNICATIONS,2013,49(13):1333-1335.
APA Wang, Wei.,Wang, Junfeng.,Zhou, Shuo.,Sun, Qi.,Ge, Zemei.,...&Li, Runtao.(2013).An efficient organocatalytic enantioselective Michael addition of aryl methyl ketones with 2-furanones: highly functionalized chiral 3,4-substituted lactones.CHEMICAL COMMUNICATIONS,49(13),1333-1335.
MLA Wang, Wei,et al."An efficient organocatalytic enantioselective Michael addition of aryl methyl ketones with 2-furanones: highly functionalized chiral 3,4-substituted lactones".CHEMICAL COMMUNICATIONS 49.13(2013):1333-1335.
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