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学科主题: 公共卫生
题名:
Suicide risk in major affective disorder: Results from a national survey in China
作者: Chen, Lin1; Liu, Yan-Hong1; Zheng, Qi-Wen2; Xiang, Yu-Tao4; Duan, Yan-ping3; Yang, Fu-de1; Wang, Gang5; Fang, Yi-Ru6; Lu, Zheng7; Yang, Hai-Chen8; Hu, Jian9; Chen, Zhi-Yu10; Huang, Yi11; Sun, Jing12; Wang, Xiao-Ping13; Li, Hui-Chun14; Zhang, Jin-Bei15; Chen, Da-Fang2; Si, Tian-Mei3
关键词: Major affective disorder ; Bipolar disorder ; Major depressive disorder ; Suicide risk
刊名: JOURNAL OF AFFECTIVE DISORDERS
发表日期: 2014-02-01
DOI: 10.1016/j.jad.2013.10.046
卷: 155, 页:174-179
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Psychiatry
研究领域[WOS]: Neurosciences & Neurology ; Psychiatry
关键词[WOS]: INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW ; BIPOLAR DISORDER ; DEPRESSIVE DISORDER ; DSM-IV ; MOOD DISORDERS ; BEHAVIOR ; PREDICTORS ; ANTIDEPRESSANTS ; METAANALYSIS ; EMBLEM
英文摘要:

Background: This study investigated suicide risk and its correlates among major affective disorder patients in China and examined possible risk factors for future suicide among individuals with major affective disorder to inform appropriate interventions and management approaches to minimize and prevent suicide.

Methods: A total of 1478 major affective disorder patients were consecutively examined in 13 mental health centers in China. The patients′ socio-demographic and clinical characteristics were recorded using a standardized protocol and data collection procedure. DSM-IV diagnoses were established using the Mini International Neuropsychiatric Interview (MINI), and suicide risk was assessed by the suicide risk module of the MINI.

Results: Of the patients, 963 (65.2%) were in the nonsuicidal risk group and 515 (34.8%) were in the suicidal risk group. Compared to major depressive disorder patients, bipolar disorder patients had higher suicide risk levels (chi(2) =10.0, df = 1, P = 0.002); however, there were no statistically significant differences (chi(2) =2.6, df = 1, P =0.1) between bipolar disorder -1 and bipolar disorder II patients. Suicide risk factors were associated with 6 variables in major affective disorder patients, as follows: male gender, unemployed, more frequent depressive episodes ( > 4 in the past year), depressive episodes with suicidal ideation and attempts, depressive episodes with psychotic symptoms, and no current antidepressant use.

Limitations: Most of the data were retrospectively collected and, therefore, subject to recall bias.

Conclusions: This study suggested that bipolar disorder patients have a higher suicide risk than major depressive disorder patients. The factors that were significantly associated with suicide risk may aid in identifying major affective disorder patients who are at risk for future suicidal behavior. (C) 2013 Elsevier B.V. All rights reserved.

语种: 英语
所属项目编号: 201303531305
项目资助者: National Key Scientific and Technological Projects (973 Program)
WOS记录号: WOS:000329574500025
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55352
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Hangzhou Seventh Peoples Hosp, Hangzhou, Zhejiang, Peoples R China
2.Peking Univ, Inst Mental Hlth, Beijing 100191, Peoples R China
3.Peking Univ, Teaching Hosp, Beijing Huilongguan Hosp, Depress Disorder Ward, Beijing 100191, Peoples R China
4.Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Beijing 100191, Peoples R China
5.Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
6.Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China
7.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Div Mood Disorders, Shanghai 200030, Peoples R China
8.Tongji Univ, Shanghai Tongji Hosp, Sch Med, Shanghai 200092, Peoples R China
9.Shenzhen Mental Hlth Ctr, Div Mood Disorders, Shenzhen, Guangdong, Peoples R China
10.Harbin Med Univ, Hosp 1, Harbin, Heilongiiang Pr, Peoples R China
11.Sichuan Univ, West China Hosp, Chengdu, Sichuan Provinc, Peoples R China
12.Nanjing Med Univ, Affiliated Brain Hosp, Nanjing, Jiangsu, Peoples R China
13.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China
14.Zhejiang Univ, Coll Med, Affiliated Hosp 2, Hangzhou, Zhejiang, Peoples R China
15.Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou, Guangdong, Peoples R China

Recommended Citation:
Chen, Lin,Liu, Yan-Hong,Zheng, Qi-Wen,et al. Suicide risk in major affective disorder: Results from a national survey in China[J]. JOURNAL OF AFFECTIVE DISORDERS,2014,155:174-179.
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