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学科主题临床医学
Reduced kidney function in acute coronary syndrome patients with undiagnosed diabetes or pre-diabetes
Liu, Hao1; Zhou, Cheng5,6; Yu, Jinming2; Jiang, Qingwu2,3; Hu, Dayi4
关键词Acute Coronary Syndrome Pre-diabetes Reduced Kidney Function Undiagnosed Diabetes
刊名NEPHROLOGY
2013-04-01
DOI10.1111/nep.12033
18期:4页:263-268
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]GLOMERULAR-FILTRATION-RATE ; CHINA HEART SURVEY ; MYOCARDIAL-INFARCTION ; GLUCOSE REGULATION ; ARTERY-DISEASE ; RENAL-FUNCTION ; US ADULTS ; MICROALBUMINURIA ; PREVALENCE ; ASSOCIATION
英文摘要

Aim Chronic kidney disease is highly prevalent in the diabetic population and it is also associated with adverse outcomes in patients with acute coronary syndrome (ACS). However, the risk of reduced kidney function (RKF) in ACS patients with undiagnosed diabetes or pre-diabetes is yet to be clear. Herein, the present study attempts to investigate the risk for RKF in ACS patients with special reference to undiagnosed diabetes and pre-diabetes, generating possible recommendations for early intervention and management in ACS patients. Methods A cross-sectional design was performed to evaluate the risk for RKF in 2232 ACS patients according to glycaemic status from the China Heart Survey between June 2005 and August 2005 by using multivariate logistic regression. Results The prevalence of RKF in ACS patients with normal glucose metabolism, pre-diabetes, undiagnosed diabetes and diagnosed diabetes was 11.6%, 17.7%, 16.7% and 28.8%, respectively. In multivariate analysis, apart from ACS patients with diagnosed diabetes, those with pre-diabetes (odds ratio=1.58, 95%:1.08-2.31) and undiagnosed diabetes (odds ratio=1.51, 95%:1.012.26) also suffered from an increased risk for RKF, compared with those with normal glucose metabolism. Stratified by ACS subtypes, the associations of RKF with ACS subtypes remained statistically significant. Conclusions The increased risk of RKF was significantly associated with undiagnosed diabetes and pre-diabetes, relative to normal glucose metabolism. Screenings for RKF among ACS patients with pre-diabetes or newly diagnosed diabetes would be highly recommended.

语种英语
WOS记录号WOS:000316916400003
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55429
专题北京大学第二临床医学院_心血管内科
作者单位1.German Canc Res Ctr, Heidelberg, Germany
2.Southern Med Univ, Nanfang Hosp, Dept Gen Surg, Guangzhou, Guangdong, Peoples R China
3.Fudan Univ, Sch Publ Hlth, Shanghai 200032, Peoples R China
4.Fudan Univ, Minist Educ, Key Lab Publ Hlth Safety, Shanghai 200032, Peoples R China
5.Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100871, Peoples R China
6.Univ Heidelberg Hosp, Heidelberg Ion Beam Therapy Ctr HIT, Heidelberg, Germany
推荐引用方式
GB/T 7714
Liu, Hao,Zhou, Cheng,Yu, Jinming,et al. Reduced kidney function in acute coronary syndrome patients with undiagnosed diabetes or pre-diabetes[J]. NEPHROLOGY,2013,18(4):263-268.
APA Liu, Hao,Zhou, Cheng,Yu, Jinming,Jiang, Qingwu,&Hu, Dayi.(2013).Reduced kidney function in acute coronary syndrome patients with undiagnosed diabetes or pre-diabetes.NEPHROLOGY,18(4),263-268.
MLA Liu, Hao,et al."Reduced kidney function in acute coronary syndrome patients with undiagnosed diabetes or pre-diabetes".NEPHROLOGY 18.4(2013):263-268.
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