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学科主题: 精神卫生
题名:
Prevalence of dementia in rural China: impact of age, gender and education
作者: Zhou, D. F.; Wu, C. S.; Qi, H.; Fan, J. H.; Sun, X. D.; Como, P.; Qiao, Y. L.; Zhang, L.; Kieburtz, K.
关键词: neuroepidemiology ; dementia ; Alzheimer&prime ; s disease
刊名: ACTA NEUROLOGICA SCANDINAVICA
发表日期: 2006-10-01
DOI: 10.1111/j.1600-0404.2006.00641
卷: 114, 期:4, 页:273-280
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: NUTRITION INTERVENTION TRIALS ; MINI-MENTAL STATE ; ALZHEIMERS-DISEASE ; POPULATION ; SHANGHAI ; LINXIAN ; DIAGNOSIS ; COMMUNITY ; KINMEN
英文摘要:

Objective - To determine the prevalence of dementia and Alzheimer′s disease (AD) in rural China. Methods - A cross-sectional study was conducted within a cohort of adults older than 50 years of age in Linxian County, China. A Chinese version of the Mini-Mental State Examination (CMMSE) was used to screen cases of possible dementia. Three different cutoff points on CMMSE were applied depending on the participant′s level of education. The participants then were given psychiatric interviews, medical and neurological examinations, and psychometric tests to ascertain the clinical diagnoses of dementia and AD. Results - Among the 16,095 participants, 5.26% were screened positive with 374 diagnosed as having dementia. Among them, AD accounted for 80.5%. The adjusted prevalence rates were 0.33%, 0.89%, 3.43%, and 8.19% in people in age groups 50-54, 55-64, 65-74, and 75 and above, respectively. The prevalence of AD correlated with the participant′s level of education, and was 2.61%, 0.94%, and 0.56% in the illiterate group, in the primary school group, and in the middle school or higher group, respectively. Adjusted by education levels a higher prevalence in women was observed in the illiterate group. Conclusions - The prevalence of dementia in this population is similar to that reported from other areas in mainland China and Taiwan with aging being a significant risk factor. After controlling for age, being a female and having received less number of years of education were associated with an higher prevalence of AD.

语种: 英语
WOS记录号: WOS:000240151100008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55460
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Beijing Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
2.Chinese Acad Med Sci, Inst Canc, Beijing 100871, Peoples R China
3.Univ Rochester, Dept Neurol, Rochester, NY USA
4.Univ Calif Davis, Med Ctr, Dept Neurol, Sacramento, CA 95817 USA
5.Sacramento VA Hosp, Dept Neurol, No Calif VA Hlth Syst, Mather, CA USA

Recommended Citation:
Zhou, D. F.,Wu, C. S.,Qi, H.,et al. Prevalence of dementia in rural China: impact of age, gender and education[J]. ACTA NEUROLOGICA SCANDINAVICA,2006,114(4):273-280.
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