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Enhanced in vitro biocompatibility of ultrafine-grained titanium with hierarchical porous surface
Zheng, C. Y.1,2,3; Nie, F. L.1,2,3; Zheng, Y. F.1,2,3; Cheng, Y.3; Wei, S. C.4; Valiev, R. Z.5
关键词Ultrafine-grained Titanium Biocompatibility Surface Modification Bioactivity Corrosion
刊名APPLIED SURFACE SCIENCE
2011-04-15
DOI10.1016/j.apsusc.2011.01.062
257期:13页:5634-5640
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Physical ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]Chemistry ; Materials Science ; Physics
关键词[WOS]NANOSTRUCTURED TITANIUM ; MECHANICAL-PROPERTIES ; CHEMICAL TREATMENT ; PURE TITANIUM ; TI ; IMPLANTS ; BONE ; VIVO ; OSSEOINTEGRATION ; MICROSTRUCTURE
英文摘要

Bulk ultrafine-grained Ti (UFG Ti) was successfully fabricated by equal-channel angular pressing (ECAP) technique in the present study, and to further improve its surface biocompatibility, surface modification techniques including sandblasting, acid etching and alkali treatment were employed to produce a hierarchical porous surface. The effect of the above surface treatments on the surface roughness, wettability, electrochemical corrosion behavior, apatite forming ability and cellular behavior of UFG Ti were systematically investigated with the coarse-grained Ti as control. Results show that UFG-Ti with surface modification had no pitting corrosion and presented low corrosion rate in simulated body fluids (SBF). The hierarchical porous surface yielded by surface modification enhanced the ability of UFG Ti to form a complete apatite layer when soaked in SBF and promoted osteoblast-like cells attachment and proliferation in vitro, which promises to have a significant impact on increasing bone-bonding ability and reducing healing time when implanted due to faster tissue integration. (C) 2011 Elsevier B. V. All rights reserved.

语种英语
WOS记录号WOS:000288205800029
项目编号31011120091 ; 51041004 ; 2007CB936103
资助机构NSFC-RFBR Cooperation ; National Natural Science Foundation of China ; State Key Development Program for Basic Research of China ; Fundamental Research Funds for the Central Universities
引用统计
被引频次:29[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55481
专题北京大学口腔医学院
作者单位1.Peking Univ, Coll Engn, Dept Adv Mat & Nanotechnol, Beijing 100871, Peoples R China
2.Peking Univ, Coll Engn, State Key Lab Turbulence & Complex Syst, Beijing 100871, Peoples R China
3.Peking Univ, Acad Adv Interdisciplinary Studies, Ctr Biomed Mat & Tissue Engn, Beijing 100083, Peoples R China
4.Peking Univ, Sch Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China
5.Ufa State Aviat Tech Univ, Inst Phys Adv Mat, Ufa, Russia
推荐引用方式
GB/T 7714
Zheng, C. Y.,Nie, F. L.,Zheng, Y. F.,et al. Enhanced in vitro biocompatibility of ultrafine-grained titanium with hierarchical porous surface[J]. APPLIED SURFACE SCIENCE,2011,257(13):5634-5640.
APA Zheng, C. Y.,Nie, F. L.,Zheng, Y. F.,Cheng, Y.,Wei, S. C.,&Valiev, R. Z..(2011).Enhanced in vitro biocompatibility of ultrafine-grained titanium with hierarchical porous surface.APPLIED SURFACE SCIENCE,257(13),5634-5640.
MLA Zheng, C. Y.,et al."Enhanced in vitro biocompatibility of ultrafine-grained titanium with hierarchical porous surface".APPLIED SURFACE SCIENCE 257.13(2011):5634-5640.
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