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An Efficient Four-Component, One-Pot Synthesis of Poly-Substituted Pyrimidines in Water
Wang Zhongqing; Ge Zemei; Cheng Tieming; Li Runtao
关键词Poly-substituted Pyrimidine Four-component One-pot Synthesis Environmentally Friendly Aqueous Medium
刊名CHINESE JOURNAL OF CHEMISTRY
2009-04-01
27期:4页:834-838
收录类别SCI ; IC ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]BIOLOGICAL EVALUATION ; KETENE DITHIOACETALS ; RECEPTORS ; LIGANDS ; HETEROCYCLES ; DERIVATIVES ; INHIBITION ; DESIGN ; ABL
英文摘要

An efficient environmentally friendly synthesis of poly-substituted pyrimidines has been developed via a four-component, one-pot reaction of malononitrile, carbon disulfide, alkyl halide and S-alkylisothiouronium salt in water at room temperature. Water as solvent, mild reaction conditions, short reaction time, simple experimental procedures, broad scope of substrates and good yields are the main advantages of this method.

语种英语
WOS记录号WOS:000265717900039
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55493
Collection北京大学药学院
北京大学药学院_化学生物学系
作者单位Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Wang Zhongqing,Ge Zemei,Cheng Tieming,et al. An Efficient Four-Component, One-Pot Synthesis of Poly-Substituted Pyrimidines in Water[J]. CHINESE JOURNAL OF CHEMISTRY,2009,27(4):834-838.
APA Wang Zhongqing,Ge Zemei,Cheng Tieming,&Li Runtao.(2009).An Efficient Four-Component, One-Pot Synthesis of Poly-Substituted Pyrimidines in Water.CHINESE JOURNAL OF CHEMISTRY,27(4),834-838.
MLA Wang Zhongqing,et al."An Efficient Four-Component, One-Pot Synthesis of Poly-Substituted Pyrimidines in Water".CHINESE JOURNAL OF CHEMISTRY 27.4(2009):834-838.
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