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学科主题: 临床医学
题名:
Post-Traumatic Malignant Glioma in a Pregnant Woman: Case Report and Review of the Literature
作者: Han, Zongli1; Du, Yanli2; Qi, Hui1; Yin, Wei1
关键词: head injury ; glioblastoma multiforme ; posttraumatic glioma ; pregnancy
刊名: NEUROLOGIA MEDICO-CHIRURGICA
发表日期: 2013-09-01
卷: 53, 期:9, 页:630-634
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Surgery
研究领域[WOS]: Neurosciences & Neurology ; Surgery
关键词[WOS]: BRAIN-TUMORS ; RISK-FACTORS ; HEAD TRAUMA ; GLIOBLASTOMA-MULTIFORME ; GROWTH ; CANCER ; RAT
英文摘要:

To add a further contribution to the literature supporting the relationship between previous head trauma and the development of glioma. We present the first case of pregnancy-related post-traumatic malignant glioma in a 29-year-old female who was admitted because of left sided hemiplegia and epilepsy due to a malignant glial tumor. She had been operated for a right frontal hematoma caused by a motorbike accident 9 years before. Neuroimaging showed a large neoplasia in the right frontal region beneath the material used for cranialplasty, and postoperative pathological revealed a glioblastoma multiforme (GBM) in continuity with the scar resulting from the trauma. While epidemiologic studies may not be conclusive, a pathologic basis has been suggested which show that trauma act as a cocarcinogen in the presence of an initiating carcinogen. Our case fulfilled the widely established criteria for brain tumors of traumatic origin. We believe that in specific cases it is reasonable to acknowledge an etiological association between head trauma and glioma. And additional factors such as pregnancy may promote the manifestation of the clinical symptoms.

语种: 英语
WOS记录号: WOS:000330100500012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55500
Appears in Collections:北京大学深圳医院_神经外科_期刊论文

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作者单位: 1.Peking Univ, Shenzhen Hosp, Dept Neurosurg, Shenzhen 518036, Guangdong, Peoples R China
2.Peking Univ, Shenzhen Hosp, Dept Nursing, Shenzhen 518036, Guangdong, Peoples R China

Recommended Citation:
Han, Zongli,Du, Yanli,Qi, Hui,et al. Post-Traumatic Malignant Glioma in a Pregnant Woman: Case Report and Review of the Literature[J]. NEUROLOGIA MEDICO-CHIRURGICA,2013,53(9):630-634.
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