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学科主题: 精神卫生
题名:
Meta-analysis of prospective memory in schizophrenia: Nature, extent, and correlates
作者: Wang, Ya1,2; Cui, Jifang3; Chan, Raymond C. K.1,2; Deng, Yongyu4; Shi, Haisong5; Hong, Xiaohong6; Li, Zhanjiang7; Yu, Xin8; Gong, Qi-yong9; Shum, David10,11
关键词: Schizophrenia ; Prospective memory ; Prefrontal lobe ; Meta-analysis
刊名: SCHIZOPHRENIA RESEARCH
发表日期: 2009-10-01
DOI: 10.1016/j.schres.2009.07.009
卷: 114, 期:1-3, 页:64-70
收录类别: SCI ; SSCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Psychiatry
研究领域[WOS]: Psychiatry
关键词[WOS]: WORKING-MEMORY ; RETROSPECTIVE-MEMORY ; EPISODIC SIMULATION ; EXECUTIVE FUNCTION ; FUTURE EVENTS ; IMPAIRMENT ; PERFORMANCE ; INTENTIONS ; DEFICITS ; NEUROCOGNITION
英文摘要:

Prospective memory (PM) is the ability to remember to carry out an intended action in the future and it is an important function for everyday living. Studies have found that the neural basis of PM is located mainly in the prefrontal lobes (particularly in Brodmann Area 10) and patients with schizophrenia have functional deficits in this area. The present study provided a meta-analytic review of PM performances in patients with schizophrenia in 11 studies. A total of 485 patients with schizophrenia and 409 controls were included. Results showed that patients with schizophrenia exhibited impairments in all time- (d = -1.33), event- (d = -0.827). and activity-based (d = -0.729) PM, with time-based PM more impaired than event-based PM. In addition, PM was found to be significantly correlated with negative symptoms (r = -0.18), general psychopathology (r = -0.168), medication dosage (r = -0.119), duration of illness (r = -0.131), age (r = -0.23), education (r = 0.249), IQ (r = 0.439) and premorbid IQ (r = 0.356). It has theoretical and clinical implications. Theoretically, the results indicate time-based PM involves more initiation than event-based PM. Clinically, the results indicate patients on high dose of antipsychotic medication and with long duration of illness need special attention from care givers for PM problems. (C) 2009 Elsevier B.V. All rights reserved.

语种: 英语
所属项目编号: 113000151 ; 09CX073007 ; KSCX2-YW-R-131 ; 07CX031003 ; 2007CB512302 ; 2007CB512305
项目资助者: Chinese Academy of Sciences ; Project-Oriented Hundred Talents Programme ; National Basic Research Programme
WOS记录号: WOS:000270758700009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55502
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
3.Beijing Normal Univ, Sch Psychol, Beijing 100875, Peoples R China
4.Zhongkai Univ Agr & Technol, Guangzhou, Guangdong, Peoples R China
5.N China Elect Power Univ, Beijing, Peoples R China
6.Shantou Univ, Mental Hlth Ctr, Shantou, Peoples R China
7.Capital Med Univ, Beijing Anding Hosp, Beijing, Peoples R China
8.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
9.Sichuan Univ, W China Sch Med, W China Hosp, Dept Radiol,Huaxi MR Res Ctr, Chengdu 610064, Peoples R China
10.Griffith Univ, Sch Psychol, Brisbane, Qld 4111, Australia
11.Griffith Univ, Griffith Inst Hlth & Med Res, Brisbane, Qld 4111, Australia

Recommended Citation:
Wang, Ya,Cui, Jifang,Chan, Raymond C. K.,et al. Meta-analysis of prospective memory in schizophrenia: Nature, extent, and correlates[J]. SCHIZOPHRENIA RESEARCH,2009,114(1-3):64-70.
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