北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学临床肿瘤学院  > 遗传学研究室  > 期刊论文
学科主题: 临床医学
题名:
Prevalence, Incidence, Clearance, and Associated Factors of Genital Human Papillomavirus Infection among Men: A Population-Based Cohort Study in Rural China
作者: Liu, Mengfei; He, Zhonghu; Zhang, Chanyuan; Liu, Fangfang; Liu, Ying; Li, Jingjing; Xu, Zhongyao; Wang, Qiyan; Hang, Dong; Shen, Na; Pan, Yaqi; Guo, Chuanhai; Cai, Hong; Ke, Yang
刊名: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
发表日期: 2014-12-01
DOI: 10.1158/1055-9965.EPI-14-0365
卷: 23, 期:12, 页:2857-2865
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Public, Environmental & Occupational Health
研究领域[WOS]: Oncology ; Public, Environmental & Occupational Health
关键词[WOS]: RISK-FACTORS ; NATURAL-HISTORY ; CERVICAL-CANCER ; HETEROSEXUAL MEN ; HPV INFECTION ; 5 CONTINENTS ; YOUNG-WOMEN ; US MEN ; DNA ; ACQUISITION
英文摘要:

Background: The natural history of human papillomavirus (HPV) infection in men on a population base has rarely been studied in general, particularly among Chinese men.

Methods: A total of 1,286 men ages 25 to 65 years from rural China were enrolled during 2009-2010 and their genital HPV infection status was assessed biannually for up to seven visits using PCR and sequencing methods. Prevalence analysis was performed among men with at least one valid HPV result (N = 1,279) and men with at least two consecutive HPV results (N = 1,059) were included in incidence and clearance analyses (median follow-up time, 31.8 months; interquartile range, 15.4-37.9 months).

Results: The prevalence and incidence of any HPV type, oncogenic, and nononcogenic HPV were 17.8%, 6.4%, 12.4%, and 14.6, 4.9, 10.8 per 1,000 person months, respectively. The median duration of infection with any HPV type, oncogenic, and nononcogenic HPV was 11.5, 6.8, and 11.5 months, respectively. The number of lifetime sexual partners was consistently associated with increased risk of prevalent and incident infection of HPV. Men ages 25 to 50 years had a higher incidence and longer duration of HPV infection than older men (51-65 years).

Conclusions and Impact: This epidemiologic investigation provides basic information of genital HPV infection among the Chinese male population; these data are crucial for the consideration of primary strategies against HPV-related carcinoma in the Chinese male and female population. (C) 2014 AACR.

语种: 英语
所属项目编号: 30930102 ; 81473033 ; 2011CB504300 ; 2012CB910800 ; 2012AA02A209 ; 2012AA022502 ; 201202014 ; 200902002 ; 7100001
项目资助者: Natural Science Foundation of China ; "973" Project of National Ministry of Science and Technology Grant ; "863" Key Projects of National Ministry of Science and Technology Grant ; Charity Project of National Ministry of Health ; Natural Science Foundation of Beijing
WOS记录号: WOS:000345967300027
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55518
Appears in Collections:北京大学临床肿瘤学院_遗传学研究室_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Canc Hosp & Inst, Genet Lab, Key Lab Carcinogenesis & Translat Res,Minist Educ, Beijing 100142, Peoples R China

Recommended Citation:
Liu, Mengfei,He, Zhonghu,Zhang, Chanyuan,et al. Prevalence, Incidence, Clearance, and Associated Factors of Genital Human Papillomavirus Infection among Men: A Population-Based Cohort Study in Rural China[J]. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION,2014,23(12):2857-2865.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Liu, Mengfei]'s Articles
[He, Zhonghu]'s Articles
[Zhang, Chanyuan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Liu, Mengfei]‘s Articles
[He, Zhonghu]‘s Articles
[Zhang, Chanyuan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace