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The responses of serum transferrin receptors to iron supplements in subjects with iron-deficiency erythropoiesis and iron-deficiency anaemia
Lin, Xiao-Ming; Tian, Wei; Ma, Le; Long, Zhu; Zhang, Juan; Shen, Xiao-Yi; Zhang, Xiao-Peng
关键词Iron Supplementation Serum Transferrin Receptors Reproductive-age Women Serum Ferritin
刊名BRITISH JOURNAL OF NUTRITION
2008-02-01
DOI10.1017/S0007114507797040
99期:2页:416-420
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Nutrition & Dietetics
研究领域[WOS]Nutrition & Dietetics
关键词[WOS]DIAGNOSIS ; THERAPY ; KNEE
英文摘要

We aimed to study the response of serum transferrin receptors (sTfR) to Fe supplementation in women of childbearing age with Fe-deficiency erythropoiesis (ME) and Fe-deficiency anaemia (IDA). Primary screening was performed in 942 women ranging in age from 18 to 45 years. After Fe-related biochemical indices such as serum ferritin, Zn protoporphyrin and Hb were determined, the subjects were divided into four groups: normal. Fe store depletion, IDE and IDA. A total of 131 women were randomly selected from the normal, IDE and IDA groups. Subsequently. seventy-six women with IDE and IDA were given various doses of Fe (14 mg/d for IDE; 28 mg/d for IDA) with ferrous L-threonate capsules for twelve consecutive weeks. After receiving Fe supplements, the levels of Fe and sTfR were determined at weeks 0. 3 6, 9 and 12. The levels of sTfR in women of childbearing age with IDE and IDA were significantly higher than those in the normal group. After receiving Fe supplements. the levels of sTfR were significantly decreased in women of childbearing age with IDE and IDA, while the levels of serum ferritin were significantly increased. In conclusion, STfR can be used as a reliable indicator for assessing the efficacy of Fe Supplements.

语种英语
WOS记录号WOS:000253045600027
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55523
专题北京大学公共卫生学院
北京大学公共卫生学院_公共卫生学院
作者单位Peking Univ, Sch Publ Hlth, Dept Nutr & Food Hyg, Beijing 100083, Peoples R China
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GB/T 7714
Lin, Xiao-Ming,Tian, Wei,Ma, Le,et al. The responses of serum transferrin receptors to iron supplements in subjects with iron-deficiency erythropoiesis and iron-deficiency anaemia[J]. BRITISH JOURNAL OF NUTRITION,2008,99(2):416-420.
APA Lin, Xiao-Ming.,Tian, Wei.,Ma, Le.,Long, Zhu.,Zhang, Juan.,...&Zhang, Xiao-Peng.(2008).The responses of serum transferrin receptors to iron supplements in subjects with iron-deficiency erythropoiesis and iron-deficiency anaemia.BRITISH JOURNAL OF NUTRITION,99(2),416-420.
MLA Lin, Xiao-Ming,et al."The responses of serum transferrin receptors to iron supplements in subjects with iron-deficiency erythropoiesis and iron-deficiency anaemia".BRITISH JOURNAL OF NUTRITION 99.2(2008):416-420.
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