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学科主题: 公共卫生
题名:
Association of obesity and atrial fibrillation among middle-aged and elderly Chinese
作者: Zhang, X.2; Zhang, S.3,4,5; Li, Y.4,5,6; Detrano, R. C.7; Chen, K.3,4,5; Li, X.4,5,6; Zhao, L.4,5,6; Benjamin, E. J.8,9; Wu, Y.1,10
关键词: atrial fibrillation ; epidemiology ; body mass index ; waist circumference
刊名: INTERNATIONAL JOURNAL OF OBESITY
发表日期: 2009-11-01
DOI: 10.1038/ijo.2009.157
卷: 33, 期:11, 页:1318-1325
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Endocrinology & Metabolism ; Nutrition & Dietetics
研究领域[WOS]: Endocrinology & Metabolism ; Nutrition & Dietetics
关键词[WOS]: BODY-MASS INDEX ; OBSTRUCTIVE SLEEP-APNEA ; RISK-FACTORS ; WAIST CIRCUMFERENCE ; INDEPENDENT RISK ; HEART-FAILURE ; DISEASE RISK ; FOLLOW-UP ; ADULTS ; ONSET
英文摘要:

Objective: To examine the associations between body mass index (BMI), waist circumference (WC) and risk of atrial fibrillation (AF) in Chinese adults.

Design, Subjects and Measurements: A cross-sectional study was conducted to explore the association between obesity and atrial fibrillation among 18 615 Chinese (10 370 females) aged 35 years and above in 2004. AF was defined by electrocardiography and history. Obesity was classified by BMI and WC, including overweight (BMI: 24.0-27.9 kg m(-2); WC: 85.0-94.9 cm for men and 80.0-89.9 cm for women) and obesity (BMI: >= 28.0kg m(-2); WC: >= 95 cm for men and >= 90 cm for women), according to the Chinese Guidelines on Prevention and Treatment of Obesity in Adults. Multivariable logistic regression was used to analyze the association between obesity and AF.

Results: Age- and sex-adjusted prevalence of AF (n = 194) was higher with increased BMI, with 0.9% for normal, 1.1% for overweight and 1.6% for obese (P(trend)< 0.01) Chinese. Compared with normal BMI, multivariable-adjusted odds ratios (ORs) were 1.2 (95% confidence interval (CI): 0.8-1.7) for overweight BMI and 1.8 (95% CI: 1.2-2.8) for obese BMI (P(trend)< 0.01). After excluding known secondary AF (valvular, postoperative and hyperthyroid) and unclassified AF, the corresponding multivariable-adjusted ORs were 1.4 (95% CI: 0.9-2.2) and 2.2 (95% CI: 1.3-3.7) (P(trend)< 0.01). The same trends were observed for WC. Multivariable-adjusted OR was 2.6 (95% CI: 1.4-4.6) for participants with both BMI and WC obesity and 1.7 (95% CI: 1.0-2.9) for participants with both BMI and WC overweight in comparison with those with both BMI and WC in the normal range.

Conclusion: Obesity, either defined by BMI or WC, was significantly associated with AF among middle-aged and elderly Chinese. International Journal of Obesity (2009) 33, 1318-1325; doi:10.1038/ijo.2009.157; published online 11 August 2009

语种: 英语
所属项目编号: 2001BA703B14 ; 2001BA703B01
项目资助者: National Tenth Five-Year Plan Science and Technology Key Projects in People&prime ; s Republic of China ; China Multicenter Collaborative Study of Cardiovascular Epidemiology
WOS记录号: WOS:000271801400015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55617
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.George Inst, Beijing, Peoples R China
2.Beijing Municipal Hlth Bur, Sci & Educ Div, Beijing, Peoples R China
3.Univ Calif Irvine, Irvine, CA USA
4.Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China
5.Chinese Acad Med Sci, Cardiovasc Inst, Ctr Arrhythmia Diag & Treatment, Beijing 100037, Peoples R China
6.Chinese Acad Med Sci, Fuwai Hosp, Beijing 100037, Peoples R China
7.Peking Union Med Coll, Beijing 100021, Peoples R China
8.Chinese Acad Med Sci, Cardiovasc Inst, Div CVD Prevent & Control Network, Beijing 100037, Peoples R China
9.Sch Med, Dept Med, Cardiol Sect, Boston, MA USA
10.Boston Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA USA

Recommended Citation:
Zhang, X.,Zhang, S.,Li, Y.,et al. Association of obesity and atrial fibrillation among middle-aged and elderly Chinese[J]. INTERNATIONAL JOURNAL OF OBESITY,2009,33(11):1318-1325.
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